Introduction: As our population ages, we are often faced with edentulose. Despite the many advantages offered by fixed prosthetic care, it is not always the most appropriate solution. Therefore care with a removable prosthetic is needed. It must be designed in a way that adequately meets the patient's needs and improves quality of life. The dental field has seen many changes in the way prosthetics are manufactured over the years. PEEK is a polymeric non-metallic material whose properties rival those of conventional materials. It is used in fixed and removable prosthetics as well as in orthodontics. In removable prosthetics, it can be used for fabrication of a wide range of constructions such as partial denture frameworks, periodontally and implant-supported telescopic crawns and shafts, acrylate partial and total denture reinforcements and obturators. Purpose: The aim of this thesis is to investigate and present the PEEK material and the fabrication of partial dentures using the subtractive method and to present the fabrication process itself. We wish to determine the suitability of PEEK material for partial dentures manufactured with subtractive method. Methods: In the theoretical part of the thesis, we used the descriptive method using literature from professional articles from professional databases, mainly in a foreign language. The databases used were Google Scholar and PubMed. In the practical part a partial denture frame made of PEEK material was designed. We also presented product design and manufacturing. Results: We printed models and used software to digitally design and create the partial denture framework. This was converted into a physical form using a subtractive milling technique. We used a PEEK material disc. After that followed postprocessing and polishing. As expected, the product achieved good results. Discussion and conclusion: The need for fabrication of removable prosthetic restorations remains high due to various factors. It is important that different materials and technologies can be used to fabricate restorations to care for patients with different needs. Metal is still the most widely used material for partial denture frameworks, but it is not an appropriate solution in certain cases. This can be resolved by using PEEK, which has the properties to provide an appropriate alternative based on patients needs.
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