Introduction: The use of metal-free materials for prosthetic rehabilitation of teeth was frequently used in the last few years. The demand for the use of these materials is mainly driven by aesthetic reasons, but also to avoid metallic taste and galvanic reactions. BioHPP material belongs to the PEEK polymer group and is its most important representative, specifically designed and optimized for use in dentistry. Purpose: The aim of this thesis is to review the existing domestic and international literature on the properties and potential uses of high-performance polymers in both fixed and removable prosthetics, and to present it as a metal-free alternative to conventional metal frameworks. Methods: The theoretical part of the thesis is based on a review of professional literature, including articles in scientific journals and books. Cobiss (Co-operative Online Bibliographic System and Services), ScienceDirect, PubMed, and Google Scholar were used for researching literature on the topic. In the practical part, the procedures for manufacturing an implant-supported full denture with a BioHPP framework and its final processing are presented. Results: A lower implant denture with a framework made of high-performance biopolymer, which is entirely metal-free, was created for the purpose of this thesis. The fabrication process was partly digital, using CAD/CAM systems, and partly analogue. After casting and processing the working model, Novaloc abutments were placed on the analogues, PEEK matrices were fitted, and the model was scanned with an extraoral laboratory scanner to obtain a digital version. It was then imported into the CAD software Exocad. It was used to design the framework, which was then milled using a milling unit. After cementing the matrices into the framework, the bite rims were fabricated, followed by the placement of the teeth in wax, and finally, the completion, finishing, cleaning, and insertion of the denture into the mouth. Discussion and conclusion: Tooth loss leads to impaired function and aesthetics of the stomatognathic system. To restore both, prosthetic rehabilitation is necessary, which can be either fixed or removable. Conventional rehabilitations involve metal alloys, which present various challenges and lead to patient dissatisfaction. Therefore, metal-free materials, which have proven to be promising, are being used increasingly. Through the modification of PEEK, BioHPP was developed, specifically intended for use in dental prosthetics. Due to its exceptional properties, it is used to a greater extent in the fabrication of implant-supported prostheses.
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