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Vrednotenje trdnih disperzij dehidriranih rdečih vin in pomožnih snovi, izdelanih s sušenjem z razprševanjem
ID Škof, Nika (Author), ID Planinšek, Odon (Mentor) More about this mentor... This link opens in a new window

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Abstract
Rdeče vino vsebuje veliko komponent, ki izkazujejo zdravju koristne učinke. Raziskave so pokazale, da zmerno uživanje vina ugodno vpliva na koagulacijski, srčno-žilni in imunski sistem. Mehanizmi, odgovorni za pozitivne učinke, so izjemno kompleksni. Pripisujemo jih antioksidativnemu delovanju. Težava je, da smo pri uživanju vina zaradi vsebnosti alkohola precej omejeni z dnevnim odmerkom. Znano je, da prekomerno uživanje alkoholnih pijač vodi v povišano tveganje za razvoj raznih zdravstvenih težav. V eksperimentalnem delu magistrske naloge smo izdelali trdne disperzije dehidriranih rdečih vin s sušenjem z razprševanjem pri enakih pogojih. Uporabili smo različna sladka in suha vina v kombinaciji z različnimi pomožnimi snovmi. Zanimal nas je vpliv deleža in vrste pomožne snovi na nastanek praškastega produkta za različna vina z namenom formulacije prehranskega dopolnila. Testirali smo 16 vin, med katerimi je bilo 13 suhih ter 3 sladka vina. Po pregledu organoleptičnih lastnosti smo kot najprimernejšo pomožno snov izbrali α-ciklodekstrin in nadaljevali z vrednotenjem lastnosti trdnih disperzij, pripravljenih s to pomožno snovjo. Opazili smo, da trdne disperzije z želenimi lastnostmi dobimo iz kombinacije suhega vina s 4,8 % vsebnostjo α-ciklodekstrina. Najožje porazdelitve velikosti delcev smo določili pri trdnih disperzijah nekaterih suhih vin s 4,8 % vsebnostjo pomožne snovi. Ta vina so bila Quercus – Cabarnet Sauvignon, Klet Brda; Jurka, Küzmič; Krasno – rdeče, Klet Brda ter domače vino “Žametno”. Pri trdnih disperzijah sladkega vina Sladki refošk, Istenič & sinova, ter trdnih disperzijah vin Merlot (Vinakoper, Klet Brda in Zalatel) smo zaznali najvišje vrednosti D90, ki so lahko posledica aglomeracije delcev. Velikost delcev trdne disperzije vina Sladki refošk, Vinakoper z 10,7 % pomožne snovi je primerljiva z vrednostmi trdnih disperzij tistih dehidriranih vin, ki so imele najmanjšo velikost in najožjo porazdelitev delcev. Dano območje velikosti izkazuje tudi najboljšo stabilnost teh trdnih disperzij. S termogravimetrično analizo smo potrdili, da sladka vina izkazujejo višjo vsebnost trdnih snovi (povprečno 9,9 %) kot suha vina (povprečno 2,9 %). Predvidevamo, da so visoke vsebnosti trdnih snovi pri sladkih vinih posledica večje vsebnosti glicerola in sladkorjev, kar je povezano z visoko higroskopnostjo njihovih trdnih disperzij. Vodna aktivnost trdnih disperzij vin s 4,8 % vsebnostjo pomožne snovi je bila zelo nizka (0,18 ali manj). Ugotovili smo, da se z višanjem vsebnosti pomožne snovi znižuje vrednost vodne aktivnosti trdnih disperzij. Vrednosti vodnih aktivnosti vseh analiziranih trdnih disperzij so bile veliko nižje od minimalne meje za razrast mikroorganizmov, ki znaša 0,6.

Language:Slovenian
Keywords:trdna disperzija, dehidrirano rdeče vino, α-ciklodekstrin, polifenoli
Work type:Master's thesis/paper
Organization:FFA - Faculty of Pharmacy
Year:2024
PID:20.500.12556/RUL-164486 This link opens in a new window
Publication date in RUL:26.10.2024
Views:69
Downloads:0
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Secondary language

Language:English
Title:Evaluation of solid dispersions with dehydrated red wines and excipients, produced by spray drying
Abstract:
Red wine contains several components with health benefits. Research showns that moderate wine consumption has beneficial effects on coagulation, cardiovascular and immune system. Mechanisms responsible are attributed to antioxidant effect and are extremely complex. The problem with consuming wine is that we are quite limited in our daily intake due to its alcohol content. It is well known that excessive consumption of alcoholic beverages leads to an increased risk of developing various health problems. In the experimental part we produced solid dispersions by spray drying under the same conditions. We used different sweet and dry wines in combination with different excipients. We were interested in the influence of the proportion and type of excipient on the formation of a powder product for different wines with the aim of formulating a food supplement. After comparing the organoleptic properties, we selected α-cyclodextrin as the most suitable excipient and proceeded to evaluate the properties of the solid dispersions prepared with α- cyclodextrin. We have observed that solid dispersions with the desired properties are obtained from a combination of dry wine with 5% α-cyclodextrin. Sweet wines have a higher sugar content, which may imply a higher hygroscopicity and consequently lead to the formation of an unprocessable product. The narrowest particle size distributions were determined for solid dispersions of some dry wines with 4,8 % excipient content. These wines were Quercus – Cabarnet Sauvignon, Klet Brda; Jurka, Küzmič; Krasno – rdeče, Klet Brda ter domače vino “Žametno”. The highest D90 values were detected in the solid dispersions of the sweet wine Sladki refošk, Istenič & sinova, and in the solid dispersions of the Merlot wines (Vinakoper, Klet Brda and Zalatel). Higher D90 values could be connected with particle agglomeration. The particle size of the solid dispersion of the wine Sladki refošk, Vinakoper with 10,7 % excipient content is comparable to the solid dispersions of those dehydrated wines which had the smallest particle size and the narrowest size distribution. This size range shows the best stability of these solid dispersions. Thermogravimetric analysis confirmed that sweet wines have a higher solids content (9,9 %) than dry wines (2,9 %). We assume that the high solids content of sweet wines is related to the higher glycerol and sugar content, which could lead to high hygroscopicity of their solid dispersions. The water activity of the solid dispersions of wines with 4,8 % excipient content was very low (0,18 or less). We found that the water activity of the solid dispersions decreases with increasing excipient content. The water activity values of all the solid dispersions analysed were well below the minimum limit for the growth of microorganisms (0,6).

Keywords:solid dispersion, dehydrated red wine, α-cyclodextrin, polyphenols

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