This diploma thesis focuses on interactions between bacteria from the genera Salmonella and Bacillus, as well as on the role of secondary metabolites in regulating the pathogenicity of bacteria from the genus Salmonella. Secondary metabolites produced by bacteria from the genus Bacillus, such as bacteriocins and polyketides, play a key role in the control of bacterial infections and impact on environment and human health. Bacteria from the genus Bacillus produce a number of antimicrobial substances with different properties. Most of these substances are silenced under laboratory conditions, and research is needed on the interactions that would trigger the synthesis of antimicrobial substances. The interactions between bacteria from the genera Bacillus and Salmonella are described, including communication, antagonism, and competitive exclusion between the two bacteria.
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