Your browser does not allow JavaScript!
JavaScript is necessary for the proper functioning of this website. Please enable JavaScript or use a modern browser.
Open Science Slovenia
Open Science
DiKUL
slv
|
eng
Search
Browse
New in RUL
About RUL
In numbers
Help
Sign in
Impact of changes in antihypertensive medication on treatment intensity at hospital discharge and 30 days afterwards
ID
Japelj, Nuša
(
Author
),
ID
Kerec Kos, Mojca
(
Author
),
ID
Jošt, Maja
(
Author
),
ID
Knez, Lea
(
Author
)
PDF - Presentation file,
Download
(869,32 KB)
MD5: 131E3159F15F841C39E60326445870CF
URL - Source URL, Visit
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2024.1376002/full
Image galllery
Abstract
Introduction: Little is known about the cumulative effect of changes in antihypertensive medications on treatment intensity. This study analyzed how changes in antihypertensive medications affect the intensity of antihypertensive treatment at hospital discharge and 30 days afterwards. Methods: A prospective observational study of 299 hospitalized adult medical patients with antihypertensive therapy was conducted. The effect of medication changes on treatment intensity was evaluated by the Total Antihypertensive Therapeutic Intensity Score (TIS). Results: At discharge, antihypertensive medications were changed in 62% of patients (184/299), resulting in a very small median reduction in TIS of −0.16. Treatment intensity was reduced more with increasing number of antihypertensive medications at admission, whereas it increased with elevated inpatient systolic blood pressure. Thirty days after discharge, antihypertensive medications were changed in 37% of patients (88/239) resulting in a median change in TIS of −0.02. Among them, 90% (79/88) had already undergone a change at discharge. The change in treatment intensity after discharge was inversely correlated with a change at discharge. Discussion: Changes in antihypertensive medication frequently occurred at discharge but had a minimal impact on the intensity of antihypertensive treatment. However, these adjustments exposed patients to further medication changes after discharge, evidencing the need for treatment reassessment in the first month post-discharge.
Language:
English
Keywords:
hypertension
,
antihypertensive agents
,
hospitalization
,
patient discharge
,
continuity of patient care
Work type:
Article
Typology:
1.01 - Original Scientific Article
Organization:
FFA - Faculty of Pharmacy
Publication status:
Published
Publication version:
Version of Record
Year:
2024
Number of pages:
10 str.
Numbering:
Vol. 15, article 1376002
PID:
20.500.12556/RUL-160059
UDC:
615.225:616.12
ISSN on article:
1663-9812
DOI:
10.3389/fphar.2024.1376002
COBISS.SI-ID:
204037891
Publication date in RUL:
14.08.2024
Views:
71
Downloads:
5
Metadata:
Cite this work
Plain text
BibTeX
EndNote XML
EndNote/Refer
RIS
ABNT
ACM Ref
AMA
APA
Chicago 17th Author-Date
Harvard
IEEE
ISO 690
MLA
Vancouver
:
Copy citation
Share:
Record is a part of a journal
Title:
Frontiers in pharmacology
Shortened title:
Front Pharmacol
Publisher:
Frontiers Media
ISSN:
1663-9812
COBISS.SI-ID:
29551833
Licences
License:
CC BY 4.0, Creative Commons Attribution 4.0 International
Link:
http://creativecommons.org/licenses/by/4.0/
Description:
This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
Secondary language
Language:
Slovenian
Keywords:
odpust bolnika
,
kontinuiteta oskrbe bolnika
,
zdravila
,
antihipertenzivi
,
hospitalizacija
Projects
Funder:
ARIS - Slovenian Research and Innovation Agency
Project number:
P1-0189
Name:
Farmacevtska tehnologija: od dostavnih sistemov učinkovin do terapijskih izidov zdravil pri otrocih in starostnikih
Funder:
ARIS - Slovenian Research and Innovation Agency
Project number:
P3-0360
Name:
Celostna obravnava alergijskih bolezni in astme v Sloveniji: od epidemiologije do genetike
Similar documents
Similar works from RUL:
Similar works from other Slovenian collections:
Back