In this diploma, I successfully synthesized two differently substituted 3-benzoylamino-2H-pyran-2-ones by one-pot synthesis method. Next, I removed the benzoylamino group on selected 3-benzoylamino-2H-pyran-2-ones, twice successfully and once unsuccessfully. Then I introduced two new protecting groups on the 3-amino end of the molecule, one with an acid chloride and the other with a double acid chloride. In the latter I successfully isolated a system where two 2H-pyran-2-ones are connected. I reacted three selected 3-benzoylamino-2H-pyran-2-one derivatives with maleic anhydride and isolated a series of bicyclo[2.2.2]octene adducts. On the selected bicyclo[2.2.2]octene adducts I tried to convert the succinic anhydride ring to the N-aminosuccinimide ring with hydrazine hydrate, but without success. In the last set I performed reactions between two selected bicyclo[2.2.2]octene adducts and two different hydrazides.
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