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Razvoj metode za določanje metil metakrilata v delovnem okolju : diplomsko delo
ID Radon, Lana (Author), ID Bavcon Kralj, Mojca (Mentor) More about this mentor... This link opens in a new window, ID Bohinc, Peter (Co-mentor), ID Fošnarič, Miha (Reviewer)

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Abstract
Uvod: Metil metakrilat (MMA) je brezbarvna bistra tekočina, ki plava na vodi oziroma se z njo rahlo meša. Hlapi, ki so težji od zraka, dražijo oči in dihala. Uporablja se v laboratorijski zobni protetiki za izdelavo ortodontskih aparatov, baz protez in odtisnih žlic. Izpostavljenost MMA negativno vpliva na zdravje laboratorijskega zobnega protetika. Povzroča draženje kože, alergijsko reakcijo, izpostavljenost hlapom pa povzroči draženje dihal. Onesnažen zrak z MMA je glavni dejavnik za razvoj zdravstvenih težav v delovnem okolju laboratorijskih zobnih protetikov. Za zmanjšanje zdravstvenih težav je priporočljiva uporaba zaščitne opreme, kot so zaščitne rokavice, očala in maska, ter urejen prezračevalni sistem v delovnem okolju. Namen: Namen diplomskega dela je razvoj metode, s katero bi lahko spremljali izhlapevanje monomera MMA v delovnem okolju, ugotoviti kakšen vpliv imajo vdihani hlapi MMA na zdravje laboratorisjkega zobnega protetika in določiti primerno zaščitno delovnega okolja, v kolikor so koncentracije MMA v delovnem okolju previsoke. Metode dela: Diplomsko delo temelji na deskriptivni metodi dela s pregledom strokovne in znanstvene literature. Prav tako smo v diplomski nalogi uporabili eksperimentalno metodo. Vzpostavili smo koncept zaprte komore s stalnimi pogoji. V zaprti komori smo merili izhlapevanje MMA, razlitega na urno steklo, v časovnem intervalu dveh ur. V drugem delu eksperimenta, smo v zaprti komori merili identiteto in koncentracijo molekul MMA v zmesi zraka. V praktičnem delu diplomskega dela smo izdelali bruksistično opornico. Rezultati: Skupaj je po prvi meritvi v 120 minutah izhlapelo 3,11 g monomere MMA, kar je enako 37,19%, po drugi meritvi je izhlapelo 2,72 g monomere MMA, kar je enako 34,35%, po tretji meritvi pa je izhlapelo 2,82 g monomere MMA, kar je enako 36,82%. V drugem delu smo merili identiteto MMA v zraku. S padanjem mase monomere MMA je rastel kromatografski vrh, do doseženega dinamičnega ravnovesja, ko se začenja vsebnost monomere MMA v zraku zmanjševat zaradi odlaganja monomere MMA na stene posode, kar je skladno z manjšanjem izgube mase opažene v gravimetrični analizi. Razprava in zaključek: Študenti laboratorijske zobne protetike in njihovi profesorji so na praktičnih vajah izpostavljeni veliki koncentraciji hlapov MMA, saj hkrati v zaprtem prostoru z monomero opravlja več ljudi hkrati. Vdihani hlapi povzročajo tveganje za ravoj astmi podobni pljučnih bolezni, prav tako vplivajo na živčni sistem, povzročajo glavobole, zaspanost in omotico. Pomanjkanje zaščitnih ukrepov, kot so prezračevalni sistemi, podaljšan čas izpostavljenosti, pomembno prispevajo k pojavu respiratornih bolezni. Varno okolje za delo z MMA je sodoben laboratorij z učinkovitim prezračevalnim sistemom.

Language:Slovenian
Keywords:diplomska dela, laboratorijska zobna protetika, metil metakrilat (MMA), hlapi, zaščitna oprema, prezračevalni sistem
Work type:Bachelor thesis/paper
Typology:2.11 - Undergraduate Thesis
Organization:ZF - Faculty of Health Sciences
Place of publishing:Ljubljana
Publisher:[L. Radon]
Year:2023
Number of pages:20 str., [1] str. pril.
PID:20.500.12556/RUL-145677 This link opens in a new window
UDC:616.31
COBISS.SI-ID:151166723 This link opens in a new window
Publication date in RUL:07.05.2023
Views:403
Downloads:71
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Secondary language

Language:English
Title:Method development for methyl methacrylate determination in the working environment : diploma work
Abstract:
Introduction: Methyl methacrylate is a colourless clear liquid that floats on water and slightly mixes with it. Vapours, which are heavier than air, irritate the eyes and respiratory system. It is used in laboratory dental prosthetics to make orthodontic appliances, denture bases, and impression trays. Exposure to MMA negatively affects the health of the dental laboratory technician. It causes skin irritation, allergic reactions, and exposure to vapours causes respiratory irritation. Polluted air with MMA is the main factor for development of health problems in the working environment of laboratory dental technicians. To reduce health issues, the use of protective equipment such as gloves, goggles, and a mask, as well as a well-ventilated work environment, is recommended. Purpose: The purpose of the thesis is to develop a method for monitoring the evaporation of MMA monomer in the workplace, determine the impact of inhaled MMA vapors on the health of the dental laboratory technician, and establish suitable protective measures in the workplace in case the concentrations of MMA in the workplace are too high. Methods: The thesis is based on a descriptive research method, which includes a review of professional and scientific literature. Additionally, an experimental method was used in the thesis. A concept of a closed chamber with constant conditions was established. In the closed chamber, the evaporation of MMA spilled on a watch glass was measured over a period of two hours. In the second part of the experiment, the identity and concentration of MMA molecules in the air mixture were measured in the closed chamber. In the practical part of the thesis, a bruxism splint was fabricated. Results: After the first measurement, a total of 3.11 g of MMA monomer evaporated in 120 minutes, which is equivalent to 37.19%. After the second measurement, 2.72 g of MMA monomer evaporated, which is equivalent to 34.35%. After the third measurement, 2.82 g of MMA monomer evaporated, which is equivalent to 36.82%. In the second part of the experiment, the identity of MMA in the air was measured. As the mass of the MMA monomer decreased, the chromatographic peak increased until the dynamic equilibrium was reached. At this point, the concentration of MMA monomer in the air began to decrease due to the deposition of MMA monomer on the walls of the container, which is consistent with the decrease in weight loss observed in the gravimetric analysis. Discussion and conclusion: Students of dental laboratory technology and their professors are exposed to high concentrations of MMA vapours during practical exercises, as several people work with the monomer in a closed space simultaneously. Inhaled vapours pose a risk for the development of asthma-like lung diseases and affect the nervous system, causing headaches, drowsiness, and dizziness. Lack of protective measures, such as ventilation systems and prolonged exposure time, significantly contribute to the onset of respiratory diseases. A safe working environment for handling MMA is a modern laboratory with an effective ventilation system.

Keywords:diploma theses, laboratory dental prosthetics, methyl methacrylate (MMA), vapours, protective equipment, ventilation system

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