Your browser does not allow JavaScript!
JavaScript is necessary for the proper functioning of this website. Please enable JavaScript or use a modern browser.
Open Science Slovenia
Open Science
DiKUL
slv
|
eng
Search
Browse
New in RUL
About RUL
In numbers
Help
Sign in
Bacillus subtilis PS-216 spores supplemented in broiler chicken drinking water reduce Campylobacter jejuni colonization and increase weight gain
ID
Šimunović, Katarina
(
Author
),
ID
Sahin, Orhan
(
Author
),
ID
Erega, Andi
(
Author
),
ID
Štefanič, Polonca
(
Author
),
ID
Zhang, Qijing
(
Author
),
ID
Mandić-Mulec, Ines
(
Author
),
ID
Smole Možina, Sonja
(
Author
),
ID
Klančnik, Anja
(
Author
)
PDF - Presentation file,
Download
(2,10 MB)
MD5: B29851300CE97B39D57D33529B998B8B
URL - Source URL, Visit
https://www.frontiersin.org/articles/10.3389/fmicb.2022.910616/full
Image galllery
Abstract
Campylobacter jejuni is the leading cause of bacterial gastroenteritis, or campylobacteriosis, in humans worldwide, and poultry serves as a major source of infection. To reduce the risk associated with C. jejuni transmission via poultry meat, effective interventions during poultry production are needed, and the use of probiotics is a promising approach. In this study, 15 Bacillus subtilis strains were initially screened for their anti-Campylobacter activities. B. subtilis PS-216 strain demonstrated the best anti-Campylobacter activity against 15 C. jejuni isolates when examined using in vitro co-cultures. To evaluate the suitability of B. subtilis PS-216 for probiotic use, its susceptibility to eight clinically important antimicrobials and simulated gastric conditions was investigated. B. subtilis PS-216 was sensitive to all of the tested antibiotics. Although vegetative cells were sensitive to gastric conditions, B. subtilis PS-216 spores were highly resistant. We further evaluated the use of a B. subtilis PS-216 spore preparation (2.5 × 10$^6$ CFU/mL water) to prevent and/or reduce C. jejuni colonization in broiler chickens in vivo. Compared to the untreated group, significantly lower Campylobacter counts were detected in caeca of broilers continuously treated with B. subtilis PS-216 spores in their drinking water. Furthermore, broilers continuously treated with B. subtilis PS-216 spores showed improved weight gain, compared to the control group. Together, these results demonstrate the potential of B. subtilis PS-216 for use in poultry to reduce C. jejuni colonization and improve weight gain.
Language:
English
Keywords:
Campylobacter jejuni
,
Bacillus subtilis
,
probiotics
,
alternative to antibiotics
,
spore-containing drinking water
,
broiler chicken
Work type:
Article
Typology:
1.01 - Original Scientific Article
Organization:
BF - Biotechnical Faculty
Publication status:
Published
Publication version:
Version of Record
Year:
2022
Number of pages:
11 str.
Numbering:
Vol. 13, art. 910616
PID:
20.500.12556/RUL-145323
UDC:
579.22/.26:579.67
ISSN on article:
1664-302X
DOI:
10.3389/fmicb.2022.910616
COBISS.SI-ID:
115015683
Publication date in RUL:
17.04.2023
Views:
605
Downloads:
83
Metadata:
Cite this work
Plain text
BibTeX
EndNote XML
EndNote/Refer
RIS
ABNT
ACM Ref
AMA
APA
Chicago 17th Author-Date
Harvard
IEEE
ISO 690
MLA
Vancouver
:
Copy citation
Share:
Record is a part of a journal
Title:
Frontiers in microbiology
Shortened title:
Front. microbiol.
Publisher:
Frontiers Research Foundation
ISSN:
1664-302X
COBISS.SI-ID:
4146296
Licences
License:
CC BY 4.0, Creative Commons Attribution 4.0 International
Link:
http://creativecommons.org/licenses/by/4.0/
Description:
This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
Secondary language
Language:
Slovenian
Keywords:
probiotiki
,
inhibicija rasti
,
sporogene bakterije
,
perutnina
Projects
Funder:
ARRS - Slovenian Research Agency
Project number:
J4-7637
Name:
Raziskave socialnih interakcij v biotehnološko in medicinsko pomembnih mikrobnih biofilmih
Funder:
ARRS - Slovenian Research Agency
Project number:
J4-2542
Name:
Mikrobne interakcije kot temelj biokontrole bakterij Campylobacter jejuni
Funder:
ARRS - Slovenian Research Agency
Project number:
J4-9299
Name:
Mehanizmi adhezije bakterij Campylobacter kot tarča za zmanjšanje antibiotske odpornosti
Funder:
ARRS - Slovenian Research Agency
Project number:
P4-0116
Name:
Mikrobiologija in biotehnologija živil in okolja
Funder:
ARRS - Slovenian Research Agency
Project number:
BI-US/19-21-105
Funder:
ARRS - Slovenian Research Agency
Project number:
BI-US/22-24-073
Similar documents
Similar works from RUL:
Similar works from other Slovenian collections:
Back