The mountain ultramarathon is a test of ultra-endurance, where competitors, in addition to the distance longer than the marathon (42,195 km), also overcome numerous climbs and descents. The "Everesting" challenge belongs also to the ultra-endurance trials, which consists of overcoming ascents and descents until the height of the vertical meters reaches the height of the world's largest mountain "Mount Everest" (8848 m). The "Everesting" challenge is a specific effort, as many vertical meters are made over a fairly short distance. After exertion such as an ultramarathon, changes occur in various areas that initially disable the re-overcoming effort. Previous studies have shown that muscle micro-injuries, inflammation, neuromuscular fatigue and hormonal balance occur, representing key short-term responses after ultramarathon. However, capacity remains reduced indefinitely even after those short-term changes have returned to the baseline. The aim of this study was to compare the effort and key responses after the »Everesting« running challenge with the effort and responses of various ultramarathons from available literature. The running tests were used to detect the reduction and return of running performance during maximum and sub-maximimal long-term efforts following the »Everesting« challenge. The study involved a subject who is an amateur mountain ultramarathon runner. The subject took measurements before the »Everesting« challenge, which served as a baseline, and measurements after the challenge, which were compared with the baseline and literature of the results after the ultramarathon. With the results of measurements during the challenge, we compared the effort during "Everesting" with the effort during the ultramarathon from the available literature. We found that the inclination of the terrain affected the intensity of effort, as the subject achieved a higher intensity during the challenge itself than was measured during the flat ultramarathon. The length of the ultramarathon has a greater impact on short-term responses after super long-term effort than inclination, as there were minor muscle micro-injuries, systemic inflammation and degraded hormonal balance during the challenge than during the ultramarathon over a longer distance with less elevation metres. The running performance monitored by running tests during maximal and sub-maxasimal long-term effort was not fully recovered even after 25 days. The main limiting factor during the recovering of running performance was the lung functions, which remained changed even after 25 days.
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