Host control by SPβ phage regulatory switch as potential manipulation strategy

Floccari, Valentina Andrea (author), Dragoš, Anna (author)

The interaction between temperate phages and their bacterial hosts has always been one of the most controversial in nature. As genetic parasites, phages need their hosts to propagate, while the host may take advantage of the genetic arsenal carried in the phage genome. This intriguing host–parasite interplay with an evident mutualistic implication could be challenged by recent discoveries of alternative phage lifestyles and regulatory systems that seem to support a manipulative strategy pursued by the phage. Through two fascinating novel mechanisms concerning the active lysogeny and a phage-encoded quorum sensing system, referred as ‘Arbitrium’, employed by SPβ-like phages of Bacilli, we propose the parasite manipulation as ecological relationship between certain temperate phages and bacteria.

• Language: English
• Work type: Article
• Typology: 1.02 - Review Article
• Organization: BF - Biotechnical Faculty
• Publication status: Published
• Publication version: Version of Record
• Year: 2023
• Number of pages: 8 str.
• Numbering: Vol. 71, art. 102260
• PID: 20.500.12556/RUL-143844
• UDC: 579.25/.26:578.347
• ISSN on article: 1369-5274
• DOI: 10.1016/j.mib.2022.102260
• COBISS.SI-ID: 135947779
• Publication date in RUL: 13.01.2023

Record is a part of a journal

• Title: Current opinion in microbiology
• Shortened title: Curr. opin. microbiol.
• Publisher: Elsevier
• ISSN: 1369-5274
• COBISS.SI-ID: 3311216

Licences

• License: CC BY 4.0, Creative Commons Attribution 4.0 International
• Link: http://creativecommons.org/licenses/by/4.0/
• Description: This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.

Secondary language

• Language: Slovenian
• Keywords: sporogene bakterije, profagi, lizogenija

Projects

• Funder: ARRS - Slovenian Research Agency
• Project number: N1-0177
• Name: Nadzor bakterijske fiziologije in interakcij s profagi

• Funder: ARRS - Slovenian Research Agency
• Project number: P4-0116
• Name: Mikrobiologija in biotehnologija živil in okolja