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Sinteza benziliden substituiranih pirazolo[1,2-a]pirazolov
ID Tomšič, Žan (Author), ID Štefane, Bogdan (Mentor) More about this mentor... This link opens in a new window

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Abstract
Klik kemija je ena izmed novejših načinov organske sinteze, pri kateri se sintetizirajo nove spojine s C–X–C vezmi. Da reakcija spada med klik kemijo, morajo biti izpolnjeni določeni pogoji. Ena izmed najbolj pomembnih reakcij v klik kemiji je 1,3-dipolarna cikloadicija, ki spada med periciklične reakcije in se uporablja za sintezo heterocikličnih sistemov z lihim številom atomov v obroču. Poleg tega sem se v uvodu posvetil azometin iminom, ki so vključeni v sintezo najrazličnejših heterociklov. Zadnji del uvoda opisuje biciklične pirazolidinone. Eksperimentalni del diplomskega dela vključuje sintezo azometin iminov iz 3-pirazolidinonov in 1,3-dipolarno cikloadicijo azometin iminov na terminalne alkine za sintezo pirazolo[1,2-a]pirazolov.

Language:Slovenian
Keywords:klik kemija, 1, 3-dipolarna cikloadicija, azometin imin, biciklični pirazolidinoni
Work type:Bachelor thesis/paper
Typology:2.11 - Undergraduate Thesis
Organization:FKKT - Faculty of Chemistry and Chemical Technology
Year:2022
PID:20.500.12556/RUL-137987 This link opens in a new window
COBISS.SI-ID:116886787 This link opens in a new window
Publication date in RUL:07.07.2022
Views:863
Downloads:119
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Secondary language

Language:English
Title:Synthesis of benzylidene substituited pyrazolo[1,2-a]pyrazoles
Abstract:
Click chemistry is one of the newer methods of organic synthesis, where new compounds with C–X–C bonds are synthesized. For a reaction to be defined as click chemistry, certain conditions must be met. One of the most important reactions in click chemistry is 1,3-dipolar cycloaddition, which is a pericyclic reaction and is used to synthesize heterocyclic systems with an odd number of atoms in the ring. In addition, in the introduction I focused on azomethine imines, which are involved in the synthesis of wide variety of heterocycles. The last part of the introduction describes bicyclic pyrazolidinones. The experimental part of the thesis includes the synthesis of azomethine imines from 3-pyrazolidinones and the 1,3-dipolar cycloaddition of azomethine imines to terminal alkynes for the synthesis of pyrazolo[1,2-a]pyrazoles.

Keywords:click chemistry, 1, 3-dipolar cycloaddition, azomethine imine, bicyclic pyrazolidinones

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