The role of immune-related miRNAs in the pathology of kidney transplantation

Boštjančič, Emanuela (author), Večerić-Haler, Željka (author), Kojc, Nika (author)

MicroRNAs (miRNAs) are members of the non-coding regulatory RNA family that play pivotal roles in physiological and pathological conditions, including immune response. They are particularly interesting as promising therapeutic targets, prognostic and diagnostic markers due to their easy detection in body fluids and stability. There is accumulating evidence that different miRNAs provide disease-specific signatures in liquid samples of distinct kidney injuries. Using experimental models and human samples, there have been numerous suggestions that immune-related miRNAs are also important contributors to the development of different kidney diseases as well as important markers for monitoring response after kidney transplantation. However, there are limited data for understanding their function in the molecular pathways of allograft pathologies. In our review, we focused on microRNAs that are related to different aspects of immune response after kidney transplantation.

• Language: English
• Keywords: microRNA (miRNA), kidney transplantation, immune response
• Work type: Article
• Typology: 1.02 - Review Article
• Organization: MF - Faculty of Medicine
• Publication status: Published
• Publication version: Version of Record
• Year: 2021
• Number of pages: 15 str.
• Numbering: Vol. 11, iss. 8, art. 1198
• PID: 20.500.12556/RUL-136014
• UDC: 616.6
• ISSN on article: 2218-273X
• DOI: 10.3390/biom11081198
• COBISS.SI-ID: 76937219
• Publication date in RUL: 06.04.2022

Record is a part of a journal

• Title: Biomolecules
• Shortened title: Biomolecules
• Publisher: MDPI
• ISSN: 2218-273X
• COBISS.SI-ID: 519952921

Licences

• License: CC BY 4.0, Creative Commons Attribution 4.0 International
• Link: http://creativecommons.org/licenses/by/4.0/
• Description: This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
• Licensing start date: 12.08.2021

Secondary language

• Language: Slovenian
• Keywords: mikroRNA (miRNA), presaditev ledvic, imunski odziv