Microbubble dynamics and jetting near tissue-phantom biointerfaces

Mur, Jaka (author), Agrež, Vid (author), Petelin, Jaka (author), Petkovšek, Rok (author)

Precise excitation of cavitation is a promising mechanism for microsurgery procedures and targeted drug delivery enhancement. The underlying phenomenon of interest, jetting behaviour of oscillating cavitation bubbles, occurs due to near-surface interactions between the boundary, liquid, and bubble. Within this study we measured boundary effects on the cavitation bubble dynamics and morphology, with an emphasis on observation and measurement of jetting behaviour near tissue-phantom biointerfaces. An important mechanism of boundary poration has been observed using time-resolved optical microscopy and explained for different tissue-phantom surface densities and Young’s modulus. Below a critical distance to the boundary, around γ = 1.0, the resulting jets penetrated the tissue-phantom, resulting in highly localized few micrometer diameter jets.

• Language: English
• Keywords: cavitation bubbles, laser breakdown, tissue phantom, sonoporation
• Work type: Article
• Typology: 1.01 - Original Scientific Article
• Organization: FS - Faculty of Mechanical Engineering
• Publication status: Published
• Publication version: Version of Record
• Year: 2022
• Number of pages: 9 str.
• Numbering: Vol. 13, no. 2, art. 449814
• PID: 20.500.12556/RUL-134937
• UDC: 532.528
• ISSN on article: 2156-7085
• DOI: 10.1364/BOE.449814
• COBISS.SI-ID: 97105923

Copyright

“© 2022 Optica Publishing Group under the terms of the Open Access Publishing Agreement. Users may use, reuse, and build upon the article, or use the article for text or data mining, so long as such uses are for noncommercial purposes and appropriate attribution is maintained. All other rights are reserved.” (Datum opombe: 10. 5. 2023)

• Publication date in RUL: 11.02.2022

Record is a part of a journal

• Title: Biomedical optics express
• Shortened title: Biomed. opt. express
• Publisher: Optica
• ISSN: 2156-7085
• COBISS.SI-ID: 24857383

Secondary language

• Language: Slovenian
• Keywords: kavitacijski mehurčki, laserski preboj, tkivni fantom, sonoporacija