Effectiveness of ultrasound-guided canal adductor blockade for chronic pain and functioning in knee osteoarthritis : a prospective longitudinal observational study

Salihović, Mensur (author), Rijavec, Boris (author), Muratagić, Anida (author), Blagus, Rok (author), Puh, Urška (author)

Background and Objective. Knee osteoarthritis is a serious epidemiological problem that causes severe pain and impairs abilities. We investigated the effects of adductor canal blockade (ACB) on chronic osteoarthritis knee pain, motor function, and mobility. Methods. Seventy-seven patients with chronic knee osteoarthritis pain received ultrasound-guided ACB with 14 ml 0.25% levobupivacaine and 100 mcg clonidine. At baseline and 1 month after the blockade, we assessed maximal and minimal pain intensity in the knee using a numeric rating scale (NRS) and the Knee Injury and Osteoarthritis Outcome Score (KOOS). The range of motion in extension and flexion (ROMext and ROMflex) and quadriceps muscle strength of both knees (QS), Timed Up and Go Test (TUG), and 30-Second Chair Stand Test (30CST) results were determined at baseline, 1 hour, 1 week, and 1 month after the blockade. Results. ACB with levobupivacaine and clonidine appeared to decrease pain severity ( 8.13 to 4.2, and 3.32 to 1.40, ). Similarly, knee ROMext decreased from 3.90 preintervention to 2.89 postintervention at 1 month, ; ROMflex decreased from 5.70 to 3.29, ; TUG time decreased from 3.22 to 2.93, <0.001; QS increased from 18.43 to 22.77, ; CST increased from 8.23 to 10.74, . The KOOS for pain (36.40 to 58.34), symptoms (52.55 to 64.32), activities of daily living functions (ADLs, 36.36 to 60.77), and quality of life (QoL, 17.87 to 30.97) also increased, all . Conclusion. ACB appeared to decrease pain and increase ambulation. If our preliminary results are reproducible in a planned randomized controlled trial, ACB could be a useful adjunctive pain therapy in patients with disabling pain due to knee OA.

• Language: English
• Keywords: osteoarthritis, knee, ultrasound-guided canal blockade
• Work type: Article
• Typology: 1.01 - Original Scientific Article
• Organization: MF - Faculty of Medicine; ZF - Faculty of Health Sciences
• Publication status: Published
• Publication version: Version of Record
• Submitted for review: 22.07.2021
• Article acceptance date: 01.12.2021
• Publication date: 22.01.2022
• Year: 2022
• Number of pages: Str. 1-10
• Numbering: Vol. 2022
• PID: 20.500.12556/RUL-134795
• UDC: 615.82/.84
• ISSN on article: 2314-6141
• DOI: 10.1155/2022/5270662
• COBISS.SI-ID: 94589699
• Publication date in RUL: 02.02.2022

Record is a part of a journal

• Title: BioMed research international
• Shortened title: Biomed Res Int
• Publisher: Hindawi Publishing
• ISSN: 2314-6141
• COBISS.SI-ID: 30624729

Licences

• License: CC BY 4.0, Creative Commons Attribution 4.0 International
• Link: http://creativecommons.org/licenses/by/4.0/
• Description: This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
• Licensing start date: 22.01.2022

Secondary language

• Language: Undetermined
• Keywords: osteoartritis, koleno, blokada kanala z ultrazvočnim vodenjem, zdravila