Choline chloride based natural deep eutectic solvents as extraction media for extracting phenolic compounds from chokeberry (Aronia melanocarpa)

Islamčević Razboršek, Maša (author), Ivanović, Milena (author), Krajnc, Peter (author), Kolar, Mitja (author)

For the isolation of selected phenolic compounds from dried chokeberries, natural deep eutectic solvents (NADESs) were investigated as a green alternative to conventionally used extraction solvents. Four types of NADESs were synthesised, with choline chloride as the hydrogen bond acceptor in combination with different hydrogen bond donors (sugars, organic acid and urea). Ultrasound-assisted extraction was used to improve the extractability of the phenolic compounds and the results were compared to those obtained with 80% methanol as the extraction media. The highest values of total phenols and total flavonoids were found in the extract obtained with choline chloride–fructose NADES (36.15 ± 3.39 mg gallic acid g$^{−1}$ dry weight (DW) and 4.71 ± 0.33 mg rutin g$^{−1}$ DW, respectively). The extraction recoveries for the individual phenolic compounds depended strongly on the phenolic compound’s structure, with relative mean values between 70% and 97%.

• Language: English
• Keywords: natural deep eutectic solvents, choline chloride, extraction, phenolic compounds, chokeberries (Aronia melanocarpa), HPLC/DAD, green solvents, ultrasound-assisted extraction, HPLC
• Work type: Article
• Typology: 1.01 - Original Scientific Article
• Organization: FKKT - Faculty of Chemistry and Chemical Technology
• Publication status: Published
• Publication version: Version of Record
• Year: 2020
• Number of pages: 14 str.
• Numbering: Vol. 25, iss. 7, art. 1619
• PID: 20.500.12556/RUL-133399
• UDC: 547.56:66.061.3
• ISSN on article: 1420-3049
• DOI: 10.3390/molecules25071619
• COBISS.SI-ID: 1538563011
• Publication date in RUL: 25.11.2021

Record is a part of a journal

• Title: Molecules
• Shortened title: Molecules
• Publisher: MDPI
• ISSN: 1420-3049
• COBISS.SI-ID: 18462981

Licences

• License: CC BY 4.0, Creative Commons Attribution 4.0 International
• Link: http://creativecommons.org/licenses/by/4.0/
• Description: This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
• Licensing start date: 01.04.2020

Secondary language

• Language: Slovenian
• Keywords: globoko evtektična topila, holin klorid, ekstrakcija, fenolne spojine, aronija, HPLC/DAD