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Uric acid and plant-based nutrition
ID
Jakše, Boštjan
(
Author
),
ID
Jakše, Barbara
(
Author
),
ID
Pajek, Maja
(
Author
),
ID
Pajek, Jernej
(
Author
)
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MD5: 3CE1A2DAE7E66A1F34675A71307DD7B5
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https://www.mdpi.com/2072-6643/11/8/1736
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Abstract
Plant-based diets (PBDs) are associated with decreased risk of morbidity and mortality associated with important noncommunicable chronic diseases. Similar to animal-based food sources (e.g., meat, fish, and animal visceral organs), some plant-based food sources (e.g., certain soy legume products, sea vegetables, and brassica vegetables) also contain a high purine load. Suboptimally designed PBDs might consequently be associated with increased uric acid levels and gout development. Here, we review the available data on this topic, with a great majority of studies showing reduced risk of hyperuricemia and gout with vegetarian (especially lacto-vegetarian) PBDs. Additionally, type of ingested purines, fiber, vitamin C, and certain lifestyle factors work in concordance to reduce uric acid generation in PBDs. Recent limited data show that even with an exclusive PBD, uric acid concentrations remain in the normal range in short- and long-term dieters. The reasonable consumption of plant foods with a higher purine content as a part of PBDs may therefore be safely tolerated in normouricemic individuals, but additional data is needed in hyperuricemic individuals, especially those with chronic kidney disease.
Language:
English
Keywords:
uric acid
,
plant-based diets
,
chronic diseases
,
purine
,
hyperuricemia
,
gout
Work type:
Article
Typology:
1.02 - Review Article
Organization:
BF - Biotechnical Faculty
FŠ - Faculty of Sport
Publication status:
Published
Publication version:
Version of Record
Year:
2019
Number of pages:
15 str.
Numbering:
Vol. 11, iss. 8, art. 1736
PID:
20.500.12556/RUL-132827
UDC:
616.6
ISSN on article:
2072-6643
DOI:
10.3390/nu11081736
COBISS.SI-ID:
6381484
Publication date in RUL:
04.11.2021
Views:
710
Downloads:
181
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Record is a part of a journal
Title:
Nutrients
Shortened title:
Nutrients
Publisher:
MDPI
ISSN:
2072-6643
COBISS.SI-ID:
2948140
Licences
License:
CC BY 4.0, Creative Commons Attribution 4.0 International
Link:
http://creativecommons.org/licenses/by/4.0/
Description:
This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
Licensing start date:
01.08.2019
Projects
Funder:
ARRS - Slovenian Research Agency
Project number:
P3-0323
Name:
Ledvične bolezni in nadomestna zdravljenja
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