Simulacija difuzije lokalnih anestetikov skozi membrano nevrona

BAČIĆ, ENEJ (author), Bulić, Patricio (mentor), Mavri, Janez (comentor)

V diplomskem delu obravnavamo problem numeričnega reševanja difuzijske enačbe na primeru prehoda lokalnih anestetikov skozi membrano nevrona. Razvili smo algoritem za simulacijo prehoda lokalnih anestetikov, nato pa še programsko kodo za sekvenčno in paralelno izvajanje simulacije. Programsko kodo smo razvili v jeziku C in jo nato paralelizirali s pomočjo OpenMP knjižnice. Rezultat diplomskega dela je program za simulacijo prehoda lokalnega anestetika skozi membrano nevrona. Prikazali smo pohitritve v primerjavi namenskega računskega vozlišča s prenosnim računalnikom in sekvenčnega programa v primerjavi s paralelnim programom. Primerjali smo čase izvajanj z uporabo različnega števila niti za izvajanje programa.

• Language: Slovenian
• Keywords: difuzijska enačba, lokalni anestetiki, nevron, paralelizacija, openMP, superračunalnik
• Work type: Bachelor thesis/paper
• Typology: 2.11 - Undergraduate Thesis
• Organization: FRI - Faculty of Computer and Information Science
• Year: 2021
• PID: 20.500.12556/RUL-130328
• COBISS.SI-ID: 77865475
• Publication date in RUL: 13.09.2021

Secondary language

• Language: English
• Title: Simulation of diffusion of local anesthetics through the neuronal membrane

Abstract

In the thesis we are solving the problem of numerical solving of the diffusion equation in the case of the passage of local anaesthetics through the membrane of the neuron. We have developed an algorithm to simulate the passage of local anaesthetics and corresponding software code for sequential and parallel execution of the simulation. The software code was developed in C programming language and then parallelized using the OpenMP library. The result of the thesis is a program that simulates the passage of local anaesthetic through the membrane of the neuron. We showed improved execution speed when using dedicated computational node in contrast to consumer laptop computer and also between sequent program solution in contrast to to a parallel one. We have also compared the run times using a different number of threads in parallel programs.

• Keywords: diffusion equation, local anesthetics, neuron, paralelization, openMP, supercomputer