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Literaturni pregled pristopov stabilizacije in vrednotenja emulzij, stabiliziranih s trdnimi delci
ID Rednak, Sara (Author), ID Planinšek, Odon (Mentor) More about this mentor... This link opens in a new window

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Abstract
Pickering emulzije so emulzije, stabilizirane s trdnimi delci, razporejenimi na medfazi olje-voda. Odkrite so bile pred stoletjem, v zadnjih desetletjih pa so postale raziskovalno izredno zanimive. V primerjavi s klasičnimi emulzijami so Pickering emulzije stabilnejše, nizko toksične in biološko bolj ugodne, saj so tako površinsko aktivne snovi odsotne ali prisotne v manjših deležih. Znanje o umeščanju delcev na medfazo se vse bolj dopolnjuje, raziskovalci pa iščejo predvsem povezavo med površinskimi značilnostmi delcev in tipom ter stabilnostjo nastale emulzije – stabilizacija emulzije tipa olje v vodi je uspešnejša s hidrofilnejšimi delci, stabilizacija emulzij tipa vode v olju pa s hidrofobnejšimi delci. Trdni delci se ireverzibilno adsorbirajo na medfazo, kar je mogoče zaradi delnega močenja delcev, ki je opredeljeno s stičnim kotom. Na stabilnost vplivajo tudi drugi dejavniki: koncentracija, velikost, oblike in površinske lastnosti delcev, vrsta oljne faze in razmerje med oljno in vodno fazo, medfazna napetost itd. Vsi ti parametri so med seboj povezani in pogosto sprememba enega parametra povzroči spremembe drugih. Pickering emulzije večinoma pripravljajo z visoko strižnimi tehnikami (rotor-stator homogenizator, visokotlačna homogenizacija in ultrazvočno razbijanje) in tehnikami nizkega striga (membransko emulgiranje in mikrofluidna tehnologija). V kozmetični industriji so emulzije eden najpogosteje uporabljenih medijev. Prednosti formulacij, stabiliziranih z delci so: večja stabilnost, boljša permeacija skozi kožo, boljši senzorični učinki, nadzorovano in počasno sproščanje aktivnih učinkovin, boljši reološki profil in trajnost. Stabilnost je mogoče doseči z uporabo različnih snovi, kot so silicijev dioksid, hitosan, celuloza in škrob. Njihove površinske lastnosti je mogoče spremeniti in izboljšati stabilnost, topnost, absorpcijo, reološke lastnosti ter senzorični občutek.

Language:Slovenian
Keywords:Pickering emulzije, trdni delci, stabilizacija, kozmetika
Work type:Bachelor thesis/paper
Organization:FFA - Faculty of Pharmacy
Year:2021
PID:20.500.12556/RUL-129911 This link opens in a new window
Publication date in RUL:09.09.2021
Views:506
Downloads:61
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Secondary language

Language:English
Title:Literature overview of characteristics and stabilisation approaches of emulsions stabilised with solid particles
Abstract:
Pickering emulsions are emulsions stabilised with solid particles, which are distributed at the oil-water interface. They were discovered a century ago but have become extremely interesting for research in recent decades. Compared to conventional emulsions, Pickering emulsions are more stable, low-toxic and biologically more favorable, as such surfactants are absent or present in smaller proportions. Knowledge of the placement of particles at the interface is increasing, and researchers are mainly looking for a connection between the surface characteristics of particles and the type and stability of the resulting emulsion - stabilisation of oil-in-water emulsion is more successful with more hydrophilic particles, stabilisation of water-in-oil emulsions with more hydrophobic particles. Solid particles are irreversibly adsorbed on the intermediate phase, which is possible due to the partial wetting of the particles, which is defined by the contact angle. Stability is also affected by other factors: concentration, size, shape and surface properties of the particles, type of oil phase and the ratio between oil and water phase, interfacial tension, etc. All of these parameters are interrelated and changing one parameter often results in changes of others. Pickering emulsions are mostly prepared by high shear techniques (rotor-stator homogenizer, high pressure homogenization and ultrasonic disintegration) and low shear techniques (membrane emulsification and microfluidic technology). In the cosmetics industry, emulsions are one of the most commonly used media. The advantages of particle-stabilised formulations are: greater stability, better permeation through the skin, better sensory effects, controlled and slow release of active ingredients, better rheological profile and durability. Stability can be achieved by using various substances such as silica, chitosan, cellulose and starch. Their surface properties can be altered and improved for stability, solubility, absorption, rheological properties, and sensory sensation.

Keywords:Pickering emulsions, solid particles, stabilisation, cosmetic

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