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Imobilizacija biokatalizatorjev v mikroreaktorje na osnovi samosestavljivih hidrogelov
Spindler, Metod (Author), Žnidaršič Plazl, Polona (Mentor) More about this mentor... This link opens in a new window

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Abstract
V zadnjih letih se je izkazalo, da imajo samosestavljivi (angl. self-assembling) hidrogeli velik potencial za uporabo v biotehnologiji, saj med drugim omogočajo zelo učinkovito imobilizacijo biokatalizatorjev, še posebno v okviru mikroreaktorjev. V delu sem predstavil osnovne koncepte mikroreaktorjev, njihove prednosti pred konvencionalnimi reaktorji ter njihovo uporabo. Poleg opisa različnih načinov imobilizacij biokatalizatorjev v mikroreaktorje, kot so imobilizacija na površino mikroreaktorja, zamreženje v gel in imobilizacija z magnetnimi delci, sem natančneje predstavil samosestavljive hidrogele. Delo obravnava pregled literature s področja različnih načinov priprave tovrstnih hidrogelov, kot tudi njihove uporabe, predvsem pri kontinuirni sintezi snovi z encimskimi mikroreaktorji.

Language:Slovenian
Keywords:mikroreaktorji, samosestavljivi hidrogeli, biokatalizatorji, imobilizacija
Work type:Bachelor thesis/paper (mb11)
Tipology:2.11 - Undergraduate Thesis
Organization:FKKT - Faculty of Chemistry and Chemical Technology
Year:2021
COBISS.SI-ID:79317251 This link opens in a new window
Views:64
Downloads:19
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Secondary language

Language:English
Title:Biocatalyst immobilization in microreactors using self-assembling hydrogels
Abstract:
In recent years, self-assembling hydrogels have been shown to have great potential for use in biotechnology, as they enable very efficient immobilization of biocatalysts, especially when used within microreactors. In this work, the basic concepts of microreactors, their advantages over conventional reactors and their potential applications are presented. Different techniques for biocatalyst immobilization in microreactors are described, such as surface immobilization, crosslinking and immobilization on magnetic particles, while self-assembling hydrogels are presented in more detail. The work includes an overview of the methods for the preparation of self-assembling hydrogels and their use in continuous synthesis with enzymatic microreactors.

Keywords:microreactors, self-assembling hydrogels, biocatalysts, immobilization

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