Alternaria mycotoxins in grains from Albania : alternariol, alternariol monomethyl ether, tenuazonic acid and tentoxin

Topi, Dritan (author), Tavčar-Kalcher, Gabrijela (author), Pavšič Vrtač, Katarina (author), Babič, Janja (author), Jakovac-Strajn, Breda (author)

The presence of four Alternaria toxins in maize and wheat harvested in 2014 and 2015 in Albania was investigated. In total, 45 samples of maize and 71 samples of wheat were collected from the country’s main producing regions. The presence of alternariol (AOH), alternariol monomethyl ether (AME), tenuazonic acid (TeA) and tentoxin (TTX) was studied by an LC-MS/MS method. The incidence of Alternaria toxins in maize was 45.2% in the year 2014 and 7.1% in 2015, and the contamination rate in wheat was 82.9% in 2014 and 86.1% in 2015. Considering maize and wheat samples together, 65.2 and 64.0% of samples were contaminated by Alternaria toxins in the harvesting years 2014 and 2015, respectively. The occurrence rate was much higher in wheat than in maize, but the concentrations were higher in maize. The highest concentration of total Alternaria toxins in maize was 1,283 μg/kg (mean 243.0 μg/kg, median 110.2 μg/kg), while the maximum concentration in wheat was 175.7 μg/kg (mean 29.9 μg/kg, median 16.5 μg/kg). TeA was the major Alternaria mycotoxin detected. It was found in 70 out of 116 samples (60.3%). Chronic exposure of the adult population in Albania to Alternaria toxins through cereal consumption was assessed by the estimated daily intake (EDI) taking into account daily consumption of wheat and maize of 380 and 4.9 g, respectively. The main contribution to chronic dietary exposure was by TeA originating from wheat, with EDIs of 88.6-94.1 ng/kg body weight (bw) per day in 2014 and 152.7-155.5 ng/kg bw per day in 2015. TTX EDIs were 7.8- 34.0 and 10.6-38.7 ng/kg bw per day in 2014 and 2015, respectively. The contribution of AOH and AME originating from wheat was 0-31.7 ng/kg bw per day. The contribution of Alternaria toxins through maize consumption was significantly lower.

• Language: English
• Keywords: mycotoxins, liquid chromatography-tandem mass spectrometry, exposure assessment
• Work type: Article
• Typology: 1.01 - Original Scientific Article
• Organization: VF - Veterinary Faculty
• Publication status: Published
• Publication version: Author Accepted Manuscript
• Year: 2019
• Number of pages: Str. 89-99
• Numbering: Vol. 12, no. 1
• PID: 20.500.12556/RUL-124490
• UDC: 543
• ISSN on article: 1875-0710
• DOI: 10.3920/WMJ2018.2342
• COBISS.SI-ID: 4734842
• Publication date in RUL: 26.01.2021

Record is a part of a journal

• Title: World mycotoxin journal
• Shortened title: World Mycotoxin J.
• Publisher: Wageningen Academic Publisher
• ISSN: 1875-0710
• COBISS.SI-ID: 2988666

Licences

• License: CC BY-NC-ND 4.0, Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
• Link: http://creativecommons.org/licenses/by-nc-nd/4.0/
• Description: The most restrictive Creative Commons license. This only allows people to download and share the work for no commercial gain and for no other purposes.
• Licensing start date: 26.01.2021

Projects

• Funder: ARRS - Slovenian Research Agency
• Project number: P4-0092
• Name: Zdravje živali, okolje in varna hrana

• Funder: EC - European Commission
• Funding programme: Erasmus Mundus