Smart structures represent a new approach to solving problems. They combine sensors and actuators into one system that responds adaptively to environmental changes. The continuous development of 3D printing technologies enables us to produce different kinds of structures and creates new opportunities in the field of research. We would like to make smart structures using 3D printing technologies because of their flexibility. This thesis focuses on the sensory part of smart structures, specifically on single process 3D printing of accelerometers. Many versions of accelerometers were designed. They're based on a cantilever beam and work on the piezoresistive phenomenon. Throughout the iterative process of design, different effects on the accelerometer's function were identified and analyzed. Furthermore, an accelerometer with relatively high sensitivity and wide measurement range was designed and experimentally validated. The presented process of design and findings of the thesis represent a step forward towards the production and industrial use of a single process 3D printed smart structures.