Občutenje utrujenosti in izvedbena utrudljivost pri bolnikih z multiplo sklerozo – pregled literature : diplomsko delo

Jaksetič, Hana (author), Puh, Urška (mentor), Kacin, Alan (reviewer)

Uvod: Utrujenost je eden najpogostejših in onesposabljajočih simptomov pri ljudeh z multiplo sklerozo. Njeno ocenjevanje je zapleteno zaradi nedoslednih in nejasnih izrazov, ki se uporabljajo za definiranje utrujenosti, in ker je odvisna od izvajane dejavnosti. Zato so predlagali opis in obravnavo dveh konstruktov utrujenosti: občutena utrujenost (tj. subjektivna zaznava zmanjšane zmožnosti) in izvedbena utrudljivost. Namen: S pregledom literature ugotoviti, na kakšne načine so merili občuteno utrujenost in izvedbeno utrudljivost pri bolnikih z multiplo sklerozo, in preučiti odnos med njima. Metode dela: Opravljen je bil pregled literature, objavljene do maja 2019. V podatkovnih zbirkah PubMed in Cochrane Library so bile iskane raziskave, v katerih so ocenjevali občuteno utrujenost in izvedbeno utrudljivost pri ljudeh z multiplo sklerozo. Rezultati: Vključenih je bilo enajst raziskav. V raziskavah so za ocenjevanje občutene utrujenosti uporabili sedem različnih samoocenjevalnih lestvic, za merjenje izvedbene utrudljivosti pa so uporabili 6-minutni test hoje (v šestih), teste mišične zmogljivosti (v treh) ali oboje (v dveh raziskavah). V šestih raziskavah so ugotovili zanemarljivo do zmerno povezanost (razpon r od –0,14 do –0,66), v petih pa ni bilo statistično pomembne povezanosti med ocenami občutene utrujenosti in meritvami izvedbene utrudljivosti. Zaključek: Pri bolnikih z multiplo sklerozo obstaja statistično pomembna, a šibka povezanost med občutenjem utrujenosti in izvedbeno utrudljivostjo. Potrebno ju je ocenjevati ločeno, z uveljavljenimi testnimi protokoli. Pri tem je smiselno upoštevati dejavnike, kot so depresija, stopnja zmanjšane telesne zmožnosti, vrsta multiple skleroze in trajanje bolezni. S standardizacijo gibalnih nalog za ocenjevanje utrudljivosti bi lahko zmanjšali raznolikost izidov v prihodnjih raziskavah. Potrebno je opraviti več raziskav, ki bi preverjale veljavnost in zanesljivost novih, še neuveljavljenih mer izvedbene utrudljivosti pri multipli sklerozi.

• Language: Slovenian
• Keywords: diplomska dela, fizioterapija, utrujenost, utrudljivost, multipla skleroza, mišična zmogljivost, 6-minutni test hoje, samoocenjevalni vprašalniki
• Work type: Bachelor thesis/paper
• Typology: 2.11 - Undergraduate Thesis
• Organization: ZF - Faculty of Health Sciences
• Place of publishing: Ljubljana
• Publisher: [H. Jaksetič]
• Year: 2020
• Number of pages: 37 str.
• PID: 20.500.12556/RUL-117997
• UDC: 615.8
• COBISS.SI-ID: 25551107
• Publication date in RUL: 08.08.2020

JAKSETIČ, Hana, 2020, Občutenje utrujenosti in izvedbena utrudljivost pri bolnikih z multiplo sklerozo – pregled literature : diplomsko delo [online]. Bachelor’s thesis. Ljubljana : H. Jaksetič. [Accessed 23 March 2025]. Retrieved from: https://repozitorij.uni-lj.si/IzpisGradiva.php?lang=eng&id=117997

Secondary language

• Language: English
• Title: Perceived fatigue and performance fatigability in people with multiple sclerosis – literature review : diploma work

Abstract

Introduction: Fatigue is one of the most common and disabling symptoms for people with multiple sclerosis. Its assessment is complicated due to inconsistent and vague terms used to define fatigue, and because it is highly task-dependent. A new fatigue taxonomy was proposed, whereby fatigue is described and treated as two different constructs: perceived fatigue (i.e. subjective perception of reduced capacity) and performance fatigability. Purpose: To investigate how perceived fatigue and performance fatigability have been assessed in people with multiple sclerosis and to examine the relationship between perceived fatigue and performance fatigability in people with multiple sclerosis using literature review. Methods: A review of the literature published until May 2019 was performed. We used databases PubMed and Cochrane Library to identify appropriate studies which assessed both perceived fatigue as well as performance fatigability in people with multiple sclerosis. Results: Eleven studies were included in this literature review. Seven different self-reporting scales were used to assess perceived fatigue, and 6-minute walking test (six), muscle performance tests (three), or both (two studies) were used to measure performance fatigability. Six studies found a statistically significant, but not high correlation (r range from –0,14 to –0,66) between perceived fatigue and performance fatigability. No statistically significant correlation was found in other five studies. Conclusions: There is statistically significant but weak association between perceived fatigue and performance fatigability in people with multiple sclerosis. They need to be assessed separately using established test protocols. Factors such as depression, clinical disability, type of multiple sclerosis, and duration of illness may influence the relationship as well. Agreeing on one or more fatigability assessment tasks could reduce the variability of results in future research. More research is needed to test the validity and reliability of new potential tests for performance fatigability in people with multiple sclerosis.

• Keywords: diploma theses, physiotherapy, fatigue, fatigability, multiple sclerosis, muscle performance, 6-minute walk test, self-reported questionnaires