In a master's thesis, in a field experiment, we evaluated the phytoremediation potential of two varieties of hemp (Cannabis sativa L.), 'Tisza' and 'Futura 75'. We selected three experimental locations in the Celje valley with different levels of soil contamination with lead, zinc and cadmium: Medlog was control location, not contaminated with Pb and Zn and slightly contaminated with Cd. In Babno, soil was medium contaminated and in Bukovžlak soil was the most contaminated with Pb, Zn and Cd. Before sowing we took soil samples from each location and determinate the basic pedological parameters (pH, organic matter content, nutrients available to plants) and lead, zinc and cadmium content in the soil. The seeds were sown with the Wintersteiger seeder in June 2017 on an 18 m2 large area. The experiment was performed in four replicates. The harvest was carried out in October 2017. We measured the biomass of each plant part separately (roots, seeds, inflorescences, separately pith and epidermis, in the two genders variety 'Tisza' separately pith and epidermis also by gender) and metal uptake by plant. Most often, the highest concentrations of Pb, Zn and Cd in both varieties were measured in inflorescences, followed by roots and seeds. The lowest uptake of Pb, Zn and Cd is in both varieties the pith and epidermis. In one growing season, phytoremediation with hemp (Cannabis sativa L.) is not effective yet, however, in a few years slightly contaminated soil could be successfully cleared with hemp.