Current trends in industry promote use of renewable and biodegradable materials that are sustainable and have a minimal impact on the environment. When it comes to materials, there is an increasing involvement in the field of nanomaterials, which have improved properties and increased applicative value. Among these materials are hydrogels based on various polymers used in the pharmaceutical industry for targeted and controlled drug release.
As part of my master's thesis, I studied the effect of composition of hydrogels from TEMPO-oxidized nanofibrillated cellulose and scleroglucan on rheological properties and release of nicotine from hydrogels based on these materials. I have concluded that ageing time and concentration are important parameters that affect the structure of hydrogels, and their influence can be studied through rheological properties. I have concluded that, in addition to the hydrogel structure, a key factor in the release of a compound is the interaction between the hydrogel and the compound.
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