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Pregled kliničnih študij o zdravju koristnih učinkih probiotičnih mlečnih izdelkov
ID Ivšek, Klara (Author), ID Rogelj, Irena (Mentor) More about this mentor... This link opens in a new window

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Abstract
Namen naloge je bil pregledati znanstvene objave kliničnih študij o zdravju koristnih učinkih probiotičnih mlečnih izdelkov in ugotoviti najbolj pogoste zdravstvene indikacije preučevanih učinkov probiotičnih mlečnih izdelkov, indikacije, pri katerih so ti najbolj učinkoviti in najverjetnejše razloge za razhajanje rezultatov. Za proučevanje zdravju koristnih učinkov probiotičnih mlečnih izdelkov so najustreznejše randomizirane, dvojno slepe in s placebom kontrolirane klinične študije. Največkrat so proučevani sevi laktobacilov in bifidobakterij, predvsem vrst Lactobacillus casei, L. paracasei, L. rhamonus, L. reuteri, L. acidophilus in Bifidobacterium bifidum, B. lactis ter B. animalis. Določeni probiotični sevi lahko zmanjšajo tveganje za bolezni zgornjih dihalnih poti in skrajšajo njihove epizode, zmanjšajo resnost prehladov in črevesnih težav pri posameznikih, izpostavljenim stresnim situacijam, zmanjšajo pojavnost in olajšajo vnetja dihal pri otrocih ter zmanjšajo število epizod z drisko in vročino pri dojenčkih, hranjenih s formulami. Probiotični mlečni izdelki lahko tudi izboljšajo gastrointestinalna nelagodja pri zdravih odraslih, imajo antidiabetične in antioksidativne lastnosti, blažijo želodčne in črevesne težave, znižajo plazemski in LDL holesterol ter koristno učinkujejo na zdravje ustne votline. Pri postavljanju končnih zdravstvenih trditev lahko ovira dejstvo, da imajo pozitiven učinek na zdravje že fermentirani mlečni izdelki z običajnimi starterskimi kulturami brez dodanih probiotičnih bakterij, ali pa je v študijah premalo udeležencev.

Language:Slovenian
Keywords:probiotiki, mlečni izdelki, vpliv na zdravje, zakonodaja, klinične študije, črevesna mikrobiota
Work type:Bachelor thesis/paper
Typology:2.11 - Undergraduate Thesis
Organization:BF - Biotechnical Faculty
Publisher:[K. Ivšek]
Year:2019
PID:20.500.12556/RUL-110434 This link opens in a new window
UDC:637.146:613.2:616
COBISS.SI-ID:5096312 This link opens in a new window
Publication date in RUL:14.09.2019
Views:995
Downloads:177
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Secondary language

Language:English
Title:Review of clinical studies considering the health effects of probiotic dairy products
Abstract:
The aim of this research was to review the scientific publications of clinical studies on the health benefits of probiotic dairy products and to identify the most common health indications of the studied effects of probiotic dairy products, the indications for which these are the most effective and probable reasons for the divergence of results. To study the health benefits of probiotic dairy products, randomized, double-blind and placebo-controlled clinical trials are most relevant. Most frequently studied probiotic strains belong to genus Lactobacillus and Bifidobacterium - species Lactobacillus casei, L. paracasei, L. rhamonus, L. reuteri, L. acidophilus and Bifidobacterium bifidum, B. lactis and B. animalis. Certain probiotic strains can reduce the risk of upper respiratory tract diseases and shorten their episodes, reduce the severity of colds and intestinal problems in healthy individuals exposed to stress, reduce the incidence and facilitate respiratory tract infections in children, reduce episodes of diarrhea and fever in infants fed with formulas. Probiotic dairy products can improve gastrointestinal discomfort in healthy adults, have antidiabetic and antioxidant properties, alleviate gastric and intestinal problems, lower plasma and LDL cholesterol and have beneficial effects on oral health. Making the final health claim may be hampered by the fact that already fermented dairy products with conventional starter cultures, without added probiotic bacteria have a positive effect on health, or that there are too few participants in the studies.

Keywords:probiotics, dairy products, health impact, legislation, clinical studies, gut microbiota

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