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Kvasovka Saccharomyces cerevisiae kot modelni organizem za preučevanje procesov staranja.
ID Fuks, Alen (Author), ID Jamnik, Polona (Mentor) More about this mentor... This link opens in a new window

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Abstract
Diplomsko delo obsega predstavitev rezultatov določenih raziskav staranja na kvasovki kot modelnem organizmu. Zaradi vse večjega deleža starega prebivalstva, postaja staranje tema, ki se vedno bolj raziskuje z namenom kakovostnejšega in daljšega življenja. Na staranje lahko vplivamo z genetskim spreminjanjem, kot je utišanje ali delecija genov, tretiranjem s kemijskimi spojinami ter s spremembo prehrane, kjer vsi načini vplivajo na poti, ki zaznavajo dostopnost hranil. V prvem delu diplomskega dela je predstavljeno, zakaj je kvasovka lahko primerni model za študij procesov staranja, nato sta razložena replikativno (RLS) in kronološko staranje (CLS). Za tem sledi razlaga procesov, ki se dogajajo preko RLS in CLS v odvisnosti od aktiviranja/deaktiviranja poti, ki zaznavajo dostopnost hranil.

Language:Slovenian
Keywords:staranje, poti zaznavanja hranil, biotehnologija, RLS, CLS
Work type:Bachelor thesis/paper
Typology:2.11 - Undergraduate Thesis
Organization:BF - Biotechnical Faculty
Publisher:[A. Fuks]
Year:2019
PID:20.500.12556/RUL-110396 This link opens in a new window
UDC:601.4:582.282.23:57.017.6(043.2)
COBISS.SI-ID:9363321 This link opens in a new window
Publication date in RUL:14.09.2019
Views:1463
Downloads:173
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Secondary language

Language:English
Title:Yeast Saccharomyces cerevisiae as a model organism for the study of aging processes.
Abstract:
This thesis consists of presenting the results of certain studies of yeast aging as a model organism. Due to the increasing share of the old population, aging is becoming a topic, which is being increasingly explored for the purpose of a better and longer life. Aging can be influenced by genetic modifications, such as shutting off genes or gene deletion, treatment with chemical compounds and with a change in diet, where all modes affect pathways, that sense nutrient availability. The first part of the thesis presents why yeast can be a suitable model for the study of aging processes and then replicative (RLS) and chronological (CLS) aging are explained. This is followed by an explanation of the processes that occur through RLS and CLS, depending on the activaton/deactivation of pathways that detect nutrient availability.

Keywords:aging, nutrient detection pathways, biotechnology, RLS, CLS

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