Vloga vitamina D v preventivi osteoporoze : diplomsko delo

Hreščak, Tjaša (author), Pandel Mikuš, Ruža (mentor)

Uvod: Vitamin D je poznan kot hranilo in hormon; je v maščobi topen vitamin, ki skrbi za razvoj imunskega sistema in kosti. V zadnjem času se veliko poroča o pomanjkanju vitamina D, kar predstavlja velik javnozdravstveni problem. Zmanjšan nos vitamina D vpliva na večjo pojavnost srčno-žilnih bolezni, rakavih obolenj, avtoimunskih bolezni in drugih. Poleg naštetega pa je hipovitaminoza D povezana tudi s pojavnostjo osteoporoze, ki je sistemska kostna bolezen, za katero je značilna nižja kostna gostota. Namen: S tem pregledom literature smo želeli predstaviti vitamin D in njegovo delovanje. Želeli smo predstaviti osteoporozo in pojasniti, kakšen je vpliv vitamina D na pojavnost osteoporoze. Metode dela: Uporabili smo deskriptivno metodo dela. Narejen je pregled slovenske in tuje literature. Uporabljena literatura se navezuje na vitamin D, osteoporozo in na njuno povezavo. Uporabljena literatura je bila objavljena med letoma 2007 in 2019. Iskana je bila v podatkovnih bazah PubMed in Science Direct. Nekaj virov je tudi iz digitalne knjižnice Univerze v Ljubljani. Razprava in zaključek: Vitamin D izboljša imunski sistem, vpliva na počutje in pojavnost srčno-žilnih bolezni, rakavih obolenj, avtoimunskih bolezni, osteoporoze in drugih. Pojavnost osteoporoze je povezana s hipovitaminozo D. Bolniki z osteoporozo bi morali imeti najmanj 20 ng/ml oziroma 50 nmol/l 25(OH)D za doseganje optimalnega zdravja kosti. Z doseganjem normalnih vrednosti vitamina D bi pri starejšem prebivalstvu dosegli boljšo kakovost življenja, manj padcev in poškodb. Normalne vrednosti vitamina D pa bi lahko zmanjšale tudi negativne simptome nekaterih bolezni, predvsem avtoimunskih.

• Language: Slovenian
• Keywords: vitamin D, osteoporoza, kakovost življenja
• Work type: Bachelor thesis/paper
• Organization: ZF - Faculty of Health Sciences
• Year: 2019
• PID: 20.500.12556/RUL-108257
• COBISS.SI-ID: 5641835
• Publication date in RUL: 22.06.2019

HREŠČAK, Tjaša, 2019, Vloga vitamina D v preventivi osteoporoze : diplomsko delo [online]. Bachelor’s thesis. [Accessed 25 March 2025]. Retrieved from: https://repozitorij.uni-lj.si/IzpisGradiva.php?lang=eng&id=108257

Secondary language

• Language: English
• Title: The role of vitamin D in the prevention of osteoporosis : diploma work

Abstract

Introduction: Vitamin D is known as a nutrient, as a hormone and is a fat-soluble vitamin that takes care of the development of the immune system and bones. Lately there is a lot of vitamin D deficiency reported, which is a major public health problem. Reduced vitamin D intake affects the incidence of cardiovascular disease, cancer, autoimmune disease, and others. In addition to this, hypovitaminosis D is also associated with the incidence of osteoporosis, which is a systemic bone disease with lower bone density. Purpose: With this review of the literature we wanted to present vitamin D and its activity, present osteoporosis, its formation and explain the impact of vitamin D on osteoporosis. Methods: We used a descriptive method of work. An overview of Slovene and foreign literature is made, which is related to vitamin D, osteoporosis and their association. The literature used was published between 2007 and 2019. References were sought in the following databases: PubMed and Science Direct. Some sources are also from the Digital Library of the University of Ljubljana. Discussion and conclusion: Vitamin D effects on general well-being, incidence of cardiovascular diseases, cancer, autoimmune diseases, osteoporosis and other diseases. The occurrence of osteoporosis is associated with hypovitaminosis D. Patients with osteoporosis should have a minimum of 20 ng/ml or 50 nmol/l 25(OH)D to achieve optimal bone health. By attaining normal vitamin D values, the older population would achieve better quality of life with fewer falls and injuries. Normal vitamin D values may also reduce the negative symptoms of some diseases, especially autoimmune ones.

• Keywords: vitamin D, osteoporosis, quality of life