Introduction: Vitamin D is known as a nutrient, as a hormone and is a fat-soluble vitamin that takes care of the development of the immune system and bones. Lately there is a lot of vitamin D deficiency reported, which is a major public health problem. Reduced vitamin D intake affects the incidence of cardiovascular disease, cancer, autoimmune disease, and others. In addition to this, hypovitaminosis D is also associated with the incidence of osteoporosis, which is a systemic bone disease with lower bone density. Purpose: With this review of the literature we wanted to present vitamin D and its activity, present osteoporosis, its formation and explain the impact of vitamin D on osteoporosis. Methods: We used a descriptive method of work. An overview of Slovene and foreign literature is made, which is related to vitamin D, osteoporosis and their association. The literature used was published between 2007 and 2019. References were sought in the following databases: PubMed and Science Direct. Some sources are also from the Digital Library of the University of Ljubljana. Discussion and conclusion: Vitamin D effects on general well-being, incidence of cardiovascular diseases, cancer, autoimmune diseases, osteoporosis and other diseases. The occurrence of osteoporosis is associated with hypovitaminosis D. Patients with osteoporosis should have a minimum of 20 ng/ml or 50 nmol/l 25(OH)D to achieve optimal bone health. By attaining normal vitamin D values, the older population would achieve better quality of life with fewer falls and injuries. Normal vitamin D values may also reduce the negative symptoms of some diseases, especially autoimmune ones.
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