Today, the dynamics of the global economy has led to 70 percent of international trade being devoted to production in global value chains, where services, raw materials, parts and components are transferred between countries before they are shaped into final products, which are later distributed to the users around the world. There is a clear trend towards increasing concentration and sharper competition among the major player on the global market. The main managers of these chains are multinational corporations. With transferring knowledge and technology, corporations include small and medium-sized enterprises, which increase the income and create new jobs, and therefore represent the backbone of the global economy. Their competitive and successful cooperation on foreign markets is determined by various factors. In this work, I examine what are the determinants that influence the success of small and medium-sized enterprises when integrating into global value chains. More fulfilled factors increase the successful integration into global value chains.