Vpliv telesne aktivnosti na parametre urejenosti sladkorne bolezni pri sladkornih bolnikih tipa 1 : magistrsko delo

Zdolšek, Anže (author), Hadžić, Vedran (mentor), Štotl, Iztok (comentor)

V magistrskem delu smo ugotavljali razlike v parametrih urejenosti sladkorne bolezni glede na telesno dejavnost pri sladkornih bolnikih tipa 1. Telesno dejavnost smo ločili na načrtovano telesno dejavnost (TD) ter na nevadbeno termogenezo (NT), torej na energijo, ki se porabi pri dejavnosti, ki ni načrtovana (hišna opravila, transport do službe, služba …). Cilji magistrskega dela so bili tudi raziskati povezavo metabolične urejenosti ter pogostosti hipoglikemij s telesno dejavnostjo pri sladkornih bolnikih tipa 1. V raziskavi je sodelovalo 109 sladkornih bolnikov tipa 1 (55 žensk, 54 moških) s povprečno starostjo 38±10 let, telesno težo 77,33±15,70 kg ter HbA1c 7,03±0,89. Sodelujoči so odgovorili na vprašalnik, ki je bil sestavljen iz vprašalnika o pojavnosti hipoglikemij (PH), vprašalnika o oceni NT ter vprašalnika o skupni telesni dejavnosti (STD). Klinični podatki, kot so pogostosti hipoglikemij, glikiran hemoglobin, inzulinska terapija, krvni tlak in maščobni profil krvi so bili zabeleženi z namenom primerjave in vplivom telesne dejavnosti. Rezultati so pokazali, da skupna telesna dejavnost ali posamičen parameter zmerno oziroma visoko intenzivne telesne dejavnosti ne vpliva na vrednost HbA1c, medtem ko je NT vplivala na višji HbA1c. Mejno smo potrdili tudi negativno povezavo stopnje NT na pogostost hipoglikemij. Stopnja NT ter visoko intenzivna telesna dejavnost pozitivno vpliva na sistoličen, ne pa tudi na diastoličen krvni tlak. Telesna dejavnost je imela vpliv tudi na maščobe v krvi, saj smo dokazali negativno povezavo visoko intenzivne telesne dejavnosti in vrednosti holesterola v krvi hkrati pa tudi negativno povezavo med visoko intenzivno telesno dejavnostjo ter stopnjo NT in LDL holesterolom. Z raziskavo smo ugotovili, da je višja stopnja NT povezana z manjšim številom hipoglikemij, nižjim sistoličnim krvnim tlakom, nižjim LDL holesterolom ter višjo vrednostjo HbA1c pri sladkornih bolnikih tipa 1.

• Language: Slovenian
• Keywords: sladkorna bolezen tipa 1, telesna dejavnost, nevadbena termogeneza, hipoglikemije
• Work type: Master's thesis/paper
• Typology: 2.09 - Master's Thesis
• Organization: FŠ - Faculty of Sport
• Year: 2018
• PID: 20.500.12556/RUL-103643
• COBISS.SI-ID: 5406641
• Publication date in RUL: 21.09.2018

ZDOLŠEK, Anže, 2018, Vpliv telesne aktivnosti na parametre urejenosti sladkorne bolezni pri sladkornih bolnikih tipa 1 : magistrsko delo [online]. Master’s thesis. [Accessed 10 June 2025]. Retrieved from: https://repozitorij.uni-lj.si/IzpisGradiva.php?lang=eng&id=103643

Secondary language

• Language: English
• Title: Effect of physical activity on metabolic control in type 1 diabetic patients

Abstract

In this master’s thesis we researched differences in metabolic control and physical activity in type 1 diabetic patients. We divided physical activity into planned physical activity (PA) and non-exercise activity thermogenesis (NEAT). NEAT is energy expended in activities that are not planned such as house chores, transport to work, profession etc. Aim of this master’s thesis was to determine correlation of metabolic control and frequency of hypoglycemia with physical activity level in type 1 diabetic patients. A total of 109 subjects with type 1 diabetes (55 women and 54 men) average age of 38±10 years, average weight of 77,33±15,70 kg, HbA1c 7,03±0,89 were included in the study. Participants were asked to complete multiple PA questionnaires, including NEAT questionnaire, WHO physical activity questionnaire and hypoglycemia questionnaire (HQ). Clinical data such as frequency of hypoglycemia, insulin therapy, HbA1c, blood pressure and serum lipid profiles were also obtained to investigate the relationship with PA and NEAT score. Results showed no statistical significance between physical activity (moderate or vigorous activity) and HbA1c while NEAT score was positively correlated with HbA1c. There was regression model predicting frequency of hypoglycemia from NEAT score was borderline negatively significant. NEAT score and vigorous physical activity positively affected on systolic blood pressure, but not on diastolic blood pressure. NEAT score and vigorous physical activity also negatively affected level of LDL-C. Our data confirmed that higher amount of NEAT is associated with lower frequency of hypoglycemia, lower systolic blood pressure, lower LDL-C and higher HbA1c in type 1 diabetic patients.

• Keywords: diabetes type 1, physical activity, non-exercise activity thermogenesis, hypoglycemia