1. Organoruthenium complexes with benzo-fused pyrithiones overcome platinum resistance in ovarian cancer cellsJerneja Kladnik, James P. C. Coverdale, Jakob Kljun, Hilke Burmeister, Petra Lippman, Francesca G. Ellis, Alan M. Jones, Ingo Ott, Isolda Romero-Canelón, Iztok Turel, 2021, original scientific article Keywords: ruthenium, pyrithione, resistance to chemotherapy, cancer, ovarian, thioredoxin Full text (file, 3,10 MB) This document has more files! More... |
2. Structural and functional characterization of an organometallic ruthenium complex as a potential myorelaxant drugTomaž Trobec, Monika C. Žužek, Kristina Sepčić, Jerneja Kladnik, Jakob Kljun, Iztok Turel, Evelyne Benoit, Robert Frangež, 2020, original scientific article Keywords: organoruthenium nitrophenanthroline complex, acetylcholinesterase, butyrylcholinesterase, glutathione S-transferase, mouse neuromuscular system, ruthenium, muscle relaxation, physiology, glutathione transferase Full text (file, 1,45 MB) This document has more files! More... |
|
4. Binding kinetics of ruthenium pyrithione chemotherapeutic candidates to human serum proteins studied by HPLC-ICP-MSKatarina Marković, Radmila Milačič, Stefan Marković, Jerneja Kladnik, Iztok Turel, Janez Ščančar, 2020, original scientific article Keywords: ruthenium-based chemotherapeutics, drug candidates, pyrithione, kinetics study, human serum, speciation analysis, CLC monolithic chromatography, CIM Protein G, DEAE disks, UV spectrometry, isotope dilution inductively coupled plasma mass spectrometry Full text (file, 2,80 MB) This document has more files! More... |
5. Conformationally driven Ru(II)-catalyzed multiple ortho-C-H bond activation in diphenylpyrazine derivatives in waterSara Hrovat, Miha Drev, Uroš Grošelj, Franc Perdih, Jurij Svete, Bogdan Štefane, Franc Požgan, 2020, original scientific article Keywords: ruthenium catalysts, heterocycles, green chemistry, microwave, direct arylation Full text (file, 2,15 MB) This document has more files! More... |
6. Catalytic stereoconvergent synthesis of homochiral β‑CF$_3$, β‑SCF$_3$, and β‑OCF$_3$ benzylic alcoholsAndrej Emanuel Cotman, Pavel A. Dub, Maša Sterle, Matic Lozinšek, Jaka Dernovšek, Živa Zajec, Anamarija Zega, Tihomir Tomašič, Dominique Cahard, 2022, original scientific article Keywords: adaptive crystals, asymmetric catalysis, density functional calculations, drug design, fluorine, hydrogenation, kinetic resolution, ruthenium, alcohols, catalysts, crystals, ketones, stereoselectivity Full text (file, 2,08 MB) This document has more files! More... |
7. Novel organoruthenium(II) complex C1 selectively inhibits butyrylcholinesterase without side effects on neuromuscular transmissionTomaž Trobec, Monika C. Žužek, Kristina Sepčić, Jerneja Kladnik, Iztok Turel, Robert Frangež, 2023, original scientific article Keywords: organoruthenium(II) complex, acetylcholinesterase, butyrylcholinesterase, mouse neuromuscular system, ruthenium, Alzheimer disease, neurodegenerative diseases Full text (file, 3,74 MB) This document has more files! More... |
8. Ruthenium complexes show potent inhibition of AKR1C1, AKR1C2, and AKR1C3 enzymes and anti-proliferative action against chemoresistant ovarian cancer cell lineJakob Kljun, Renata Pavlič, Eva Hafner, Tanja Lipec, Sara Moreno-Da Silva, Primož Tič, Iztok Turel, Tomaž Büdefeld, Jure Stojan, Tea Lanišnik-Rižner, 2022, original scientific article Keywords: ruthenium complexes, synthesis, crystal structure, anticancer, aldo-keto reductase, enzyme inhibition Full text (file, 1,85 MB) This document has more files! More... |
9. Hydrogen-bonding ability of Noyori–Ikariya catalysts enables stereoselective access to CF$_3$-substituted syn-1,2-diols via dynamic kinetic resolutionMaša Sterle, Matej Huš, Matic Lozinšek, Anamarija Zega, Andrej Emanuel Cotman, 2023, other scientific articles Keywords: asymmetric catalysis, DFT, drug design, fluorine, hydrogenation, kinetic resolution, ruthenium, catalysts, ketones, noncovalent interactions, redox reactions, stereoselectivity Full text (file, 2,30 MB) This document has more files! More... |
10. Catalytic performance of Noyori–Ikariya-type ruthenium complex with tethered syn-ULTAM ligand for the asymmetric transfer hydrogenation of ketonesSimona Hašanová, Jernej Cingl, Tihomir Tomašič, Andrej Emanuel Cotman, 2024, original scientific article Keywords: asymmetric synthesis, ruthenium, hydrogenation, alcohol Full text (file, 599,43 KB) This document has more files! More... |