61. Potent DNA gyrase inhibitors bind asymmetrically to their target using symmetrical bifurcated halogen bondsAnja Kolarič, Thomas Germe, Martina Hrast, Clare E. M. Stevenson, David M. Lawson, Nicolas P. Burton, Judit Vörös, Anthony Maxwell, Nikola Minovski, Marko Anderluh, 2021, original scientific article Keywords: antibacterials, DNA gyrase inhibitors, drug discovery, Staphylococcus aureus, intercalators, novel bacterial topoisomerase inhibitors, NBTIs, symmetrical bifurcated halogen bonds, crystal structure, novel NBTIs mechanism of action, antimicrobials, DNA-binding proteins, drug development, X-ray crystallography Full text (file, 2,00 MB) This document has more files! More... |
62. Standardization of esophageal adenocarcinoma in vitro model and its applicability for model drug testingLarisa Tratnjek, Nadica Sibinovska, Slavko Kralj, Darko Makovec, Katja Kristan, Mateja Erdani-Kreft, 2021, original scientific article Keywords: esophageal adenocarcinoma, FLO-1 cell line, disease pathophysiology, biological techniques, cancer, cell biology, diseases, drug discovery, engineering, oncology Full text (file, 16,48 MB) This document has more files! More... |
63. Strukturno podprto načrtovanje, sinteza in biološko vrednotenje novih zaviralcev O-β-N-acetilglukozaminil transferazeElena Maria Loi, 2023, doctoral dissertation Keywords: O-GlcNAcylation, OGT, OGA, OGT inhibitors, posttranslational modifications, computational drug design, virtual screening, ester hydrolysis, metabolic stability. Full text (file, 20,68 MB) |
64. Strukturno podprto načrtovanje, sinteza in biološko vrednotenje novih zaviralcev O-β-N-acetilglukozaminil transferazeElena Maria Loi, 2023, doctoral dissertation Keywords: O-GlcNAcylation, OGT, OGA, OGT inhibitors, posttranslational, modifications, computational drug design, virtual screening, ester hydrolysis, metabolic stability Full text (file, 20,68 MB) |
65. Mesenchymal stem/stromal cells may decrease success of cancer treatment by inducing resistance to chemotherapy in cancer cellsTaja Železnik Ramuta, Mateja Erdani-Kreft, 2022, review article Keywords: mesenchymal stem/stromal cells, tumour microenvironment, cancer therapy, tumour stroma, cancers, drug resistance Full text (file, 936,72 KB) This document has more files! More... |
66. A set of experimentally validated decoys for the human CC chemokine receptor 7 (CCR7) obtained by virtual screeningMatic Proj, Steven De Jonghe, Tom Van Loy, Marko Jukič, Anže Meden, Luka Ciber, Črtomir Podlipnik, Uroš Grošelj, Janez Konc, Dominique Schols, Stanislav Gobec, 2022, original scientific article Keywords: virtual screening, decoys, chemical library, computer-aided drug design, CCR7, GPCR Full text (file, 2,30 MB) This document has more files! More... |
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68. Water-soluble chitosan eases development of mucoadhesive buccal films and wafers for childrenKarin Korelc, Bjarke Strøm Larsen, Mirjana Gašperlin, Ingunn Tho, 2023, original scientific article Keywords: biocompatibility, HT29-MTX cells, organoleptic properties, patient-centric drug delivery, prednisolone, Viscosan Full text (file, 2,63 MB) This document has more files! More... |
69. Clonal mast cell disorders and hereditary α-tryptasemia as risk factors for anaphylaxisMark Kačar, Matija Rijavec, Julij Šelb, Peter Korošec, 2023, review article Keywords: anaphylaxis, venom, food, drugs, tryptase, mast cells, KIT p.D816V, hereditary α-tryptasemia, hypersensitivity, diagnosis, food hypersensitivity, drug hypersensitivity Full text (file, 3,53 MB) This document has more files! More... |
70. Hydrogen-bonding ability of Noyori–Ikariya catalysts enables stereoselective access to CF$_3$-substituted syn-1,2-diols via dynamic kinetic resolutionMaša Sterle, Matej Huš, Matic Lozinšek, Anamarija Zega, Andrej Emanuel Cotman, 2023, other scientific articles Keywords: asymmetric catalysis, DFT, drug design, fluorine, hydrogenation, kinetic resolution, ruthenium, catalysts, ketones, noncovalent interactions, redox reactions, stereoselectivity Full text (file, 2,30 MB) This document has more files! More... |