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14. CDR1 composition can affect nanobody recombinant expression yieldsMarco Orlando, Sara Fortuna, Sandra Oloketuyi, Gregor Bajc, Adi Goldenzweig, Ario De Marco, 2021, original scientific article Keywords: nanobodies, in silico engineering, mutagenesis, nanobody CDRs, in silico modeling, rational mutagenesis, nanobody engineering Full text (file, 2,37 MB) This document has more files! More... |
15. Crystal structure of RahU, an aegerolysin protein from the human pathogen Pseudomonas aeruginosa, and its interaction with membrane ceramide phosphorylethanolamineEva Kočar, Tea Lenarčič, Vesna Hodnik, Anastasija Panevska, Yunjie Huang, Gregor Bajc, Rok Kostanjšek, Anjaparavanda P. Naren, Peter Maček, Gregor Anderluh, Kristina Sepčić, Marjetka Podobnik, Matej Butala, 2021, original scientific article Keywords: aegerolysins, crystal structure of RahU, ceramide phosphorylethanolamine, biochemistry, lipids, membrane lipids, membrane proteins, microbiology, proteins, sphingolipids, structural biology, X-ray crystallography Full text (file, 2,95 MB) This document has more files! More... |
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17. Inhibition of the SARS-CoV-2 3CL$^{pro}$ main protease by plant polyphenolsMiha Bahun, Marko Jukič, Domen Oblak, Luka Kranjc, Gregor Bajc, Matej Butala, Krištof Bozovičar, Tomaž Bratkovič, Črtomir Podlipnik, Nataša Poklar Ulrih, 2022, original scientific article Keywords: edible plants, polyphenols, COVID-19, SARS-CoV-2, 3CL$^{pro}$, protease inhibitor Full text (file, 2,14 MB) This document has more files! More... |
18. Effect of humanizing mutations on the stability of the llama single-domain variable regionMiguel A. Soler, Barbara Medagli, Jiewen Wang, Sandra Oloketuyi, Gregor Bajc, He Huang, Sara Fortuna, Ario De Marco, 2021, original scientific article Keywords: nanobody framework, modeling, nanobody humanization, CDR grafting Full text (file, 2,00 MB) This document has more files! More... |
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20. Discovery of a fragment hit compound targeting D-Ala:D-Ala ligase of bacterial peptidoglycan biosynthesisMatic Proj, Martina Hrast, Gregor Bajc, Rok Frlan, Anže Meden, Matej Butala, Stanislav Gobec, 2023, original scientific article Keywords: fragment-based drug discovery, hit triage, inhibitors, antibacterial agents Full text (file, 1,79 MB) This document has more files! More... |