1. Harnessing the untapped potential of nucleotide‐binding oligomerization domain ligands for cancer immunotherapySanja Nabergoj, Irena Mlinarič-Raščan, Žiga Jakopin, 2019, review article Keywords: adjuvants, cancer immunotherapy, immunotherapeutics, NOD1 agonists, NOD1 antagonists, NOD2 agonists, NOD2 antagonists Full text (file, 2,15 MB) This document has more files! More... |
2. Glucagon-like peptide-1 receptor agonists in the management of type 2 diabetes mellitus and obesityJasna Klen, Vita Dolžan, 2022, review article Keywords: type 2 diabetes mellitus, obesity, GLP‐1 receptor agonists, incretins, cardiovascular safety, genetic polymorphisms Full text (file, 1,07 MB) This document has more files! More... |
3. The activation of GPR27 increases cytosolic L-lactate in 3T3 embryonic cells and astrocytesDorian Dolanc, Tomaž Mark Zorec, Zala Smole, Anja Maver, Anemari Horvat, Thanigaimalai Pillaiyar, Saša Trkov, Nina Vardjan, Marko Kreft, Helena Haque Chowdhury, Robert Zorec, 2022, original scientific article Keywords: 3T3 embryonic cells, astrocytes, aerobic glycolysis, cytosolic L-lactate, FRET nanosensor, G-protein-coupled receptors, GPR27, agonists Full text (file, 24,11 MB) This document has more files! More... |
4. Discovery of desmuramylpeptide NOD2 agonists with single-digit nanomolar potencySamo Guzelj, Špela Janež, Žiga Jakopin, 2022, original scientific article Keywords: NOD2, desmuramylpeptide, immunostimulant, adamantane, PBMC cytotoxicity, K562, agonists, cells, peptides and proteins, reaction products, toxicological synergy Full text (file, 2,68 MB) This document has more files! More... |
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6. Preliminary results on novel adjuvant combinations suggest enhanced immunogenicity of whole inactivated pandemic influenza vaccinesAllegra Pelettǎ, Aurélie Marmy, Samo Guzelj, Alcidia Ramos Barros, Žiga Jakopin, Gerrit Borchard, 2024, original scientific article Keywords: pandemic influenza vaccine, adjuvant, hybrid PLGA nanoparticle, tomatine saponin, NOD2 agonists, formulation, immunogenicity Full text (file, 2,33 MB) This document has more files! More... |
7. Distinctive immune signatures driven by structural alterations in desmuramylpeptide NOD2 agonistsŠpela Janež, Samo Guzelj, Petra Kocbek, Eveline A. de Vlieger, Bram Slütter, Žiga Jakopin, 2024, original scientific article Keywords: agonists, cells, peptides, proteins, reaction products, toxicity Full text (file, 4,81 MB) This document has more files! More... |
8. Linker chemistry and connectivity fine-tune the immune response and kinetic solubility of conjugated NOD2/TLR7 agonistsŠpela Janež, Samo Guzelj, Žiga Jakopin, 2024, original scientific article Keywords: agonists, amines, conjugate acid-base pairs, peptides, proteins, solubility Full text (file, 2,69 MB) This document has more files! More... |