1. Inhibition of the SARS-CoV-2 3CL$^{pro}$ main protease by plant polyphenolsMiha Bahun, Marko Jukič, Domen Oblak, Luka Kranjc, Gregor Bajc, Matej Butala, Krištof Bozovičar, Tomaž Bratkovič, Črtomir Podlipnik, Nataša Poklar Ulrih, 2022, original scientific article Keywords: edible plants, polyphenols, COVID-19, SARS-CoV-2, 3CL$^{pro}$, protease inhibitor Full text (file, 2,14 MB) This document has more files! More... |
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3. Focused peptide library screening as a route to a superior affinity ligand for antibody purificationKrištof Bozovičar, Barbara Jenko Bizjan, Anže Meden, Jernej Kovač, Tomaž Bratkovič, 2021, original scientific article Keywords: biochemistry, biophysics, biotechnology, chemical biology Full text (file, 2,17 MB) This document has more files! More... |
4. ATP-competitive inhibitors of human DNA topoisomerase IIα with improved antiproliferative activity based on N-phenylpyrrolamide scaffoldŽiga Skok, Martina Durcik, Živa Zajec, Darja Gramec, Krištof Bozovičar, Anja Pišlar, Tihomir Tomašič, Anamarija Zega, Lucija Peterlin-Mašič, Danijel Kikelj, Nace Zidar, Janez Ilaš, 2023, original scientific article Keywords: anticancer drugs, ATP-competitive inhibitors, catalytic inhibitor, cytotoxicity, human DNA topoisomerase II Full text (file, 2,83 MB) This document has more files! More... |
5. DNA-encoded library screening on two validated enzymes of the peptidoglycan biosynthetic pathwayMatic Proj, Krištof Bozovičar, Martina Hrast, Rok Frlan, Stanislav Gobec, 2022, original scientific article Keywords: antibacterial agents, DNA-encoded library, screening, inhibitors Full text (file, 1,04 MB) This document has more files! More... |
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7. Psoralen derivatives as inhibitors of mycobacterium tuberculosis proteasomeKaja Rožman, Evan M. Alexander, Eva Ogorevc, Krištof Bozovičar, Izidor Sosič, Courtney C. Aldrich, Stanislav Gobec, 2020, original scientific article Keywords: protein degradation, proteasome, Mycobacterium tuberculosis, psoralens, nonpeptidic proteasome inhibitors Full text (file, 6,28 MB) This document has more files! More... |
8. Small and simple, yet sturdyKrištof Bozovičar, Tomaž Bratkovič, 2021, review article Keywords: constrained peptides, macrocycles, crosslinking, enzymatic cyclization, stapling, hairpin loop Full text (file, 2,46 MB) This document has more files! More... |
9. Fragment-sized thiazoles in fragment-based drug discovery campaignsMatic Proj, Martina Hrast, Damijan Knez, Krištof Bozovičar, Katarina Grabrijan, Anže Meden, Stanislav Gobec, Rok Frlan, 2022, original scientific article Keywords: thiazoles, hit profiling, promiscuous compounds, frequent hitters, privileged scaffolds, fragments Full text (file, 2,30 MB) This document has more files! More... |
10. CRISPR technologies in Chinese hamster ovary cell line engineeringKatja Glinšek, Krištof Bozovičar, Tomaž Bratkovič, 2023, review article Keywords: Chinese hamster ovary cells, cell line development, CRISPR-Cas, genome editing, glycoengineering, augmenting productivity Full text (file, 1,45 MB) This document has more files! More... |