1. Action of clathrodin and analogues on voltage-gated sodium channelsSteve Peigneur, Aleš Žula, Nace Zidar, Fiona Chan-Porter, Robert Kirby, David J. Madge, Janez Ilaš, Danijel Kikelj, Jan Tytgat, 2014, original scientific article Keywords: clathrodin, oroidin, hymenidin, voltage-gated sodium channels, sodium channel modulator, sponge Full text (file, 738,85 KB) This document has more files! More... |
2. Antimicrobial activity of the marine alkaloids, clathrodin and oroidin, and their synthetic analoguesNace Zidar, Sofia Montalvão, Žiga Hodnik, Dorota A. Nawrot, Aleš Žula, Janez Ilaš, Danijel Kikelj, Päivi Tammela, Lucija Peterlin-Mašič, 2014, original scientific article Keywords: marine alkaloid, Agelas, antimicrobial, antibacterial, antifungal, pyrrole-2-aminoimidazole, oroidin, clathrodin Full text (file, 935,08 KB) This document has more files! More... |
3. Synthesis and evaluation of spumigin analogues library with thrombin inhibitory activityAleš Žula, Izabela Będziak, Danijel Kikelj, Janez Ilaš, 2018, original scientific article Keywords: marine products, natural peptides, peptidomimetics, thrombin inhibition Full text (file, 9,50 MB) This document has more files! More... |
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5. Discovery of compounds with viscosity-reducing effects on biopharmaceutical formulations with monoclonal antibodiesMatic Proj, Mitja Zidar, Blaž Lebar, Nika Strašek Benedik, Goran Miličić, Aleš Žula, Stanislav Gobec, 2022, original scientific article Keywords: viscosity, protein formulations, biopharmaceuticals, viscosity-reducing agents, computational screening Full text (file, 2,19 MB) This document has more files! More... |
6. The search for novel proline analogs for viscosity reduction and stabilization of highly concentrated monoclonal antibody solutionsMonika Prašnikar, Matic Proj, Maja Bjelošević Žiberna, Blaž Lebar, Benjamin Knez, Nika Kržišnik, Robert Roškar, Stanislav Gobec, Iztok Grabnar, Aleš Žula, Pegi Ahlin Grabnar, 2024, original scientific article Keywords: proline analogs, monoclonal antibodies, subcutaneous administration, viscosity reducers, high concentration Full text (file, 6,86 MB) This document has more files! More... |
7. Alternative buffer systems in biopharmaceutical formulations and their effect on protein stabilityBlaž Lebar, Mitja Zidar, Janez Mravljak, Roman Šink, Aleš Žula, Stane Pajk, 2024, original scientific article Keywords: biopharmaceuticals, buffer, stress, aggregates, alternative buffers, stability Full text (file, 2,17 MB) This document has more files! More... |
8. A multifaceted approach to understanding protein-buffer interactions in biopharmaceuticalsBlaž Lebar, Maria Orehova, Boštjan Japelj, Ernest Šprager, Rok Podlipec, Tilen Knaflič, Iztok Urbančič, Benjamin Knez, Mitja Zidar, Jure Cerar, Janez Mravljak, Aleš Žula, Denis Arčon, Janez Plavec, Stane Pajk, 2025, original scientific article Keywords: buffer, interaction, methyl fingerprinting, molecular dynamics, monoclonal antibody, nuclear magnetic resonance Full text (file, 4,94 MB) This document has more files! More... |