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1. Primerjava marketinške zanimivosti moškega in ženskega športa
Živa Zajec, 2007, undergraduate thesis

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2. Biološko vrednotenje protirakavega delovanja zaviralcev C-končne domene Hsp90
Teja Kosmač, 2022, master's thesis/paper

Keywords: zaviralci Hsp90, rak, C-končna domena
Full text (file, 2,08 MB)

3. Sinteza in biološko vrednotenje halogeniranih piperidinskih zaviralcev proteina Hsp90 z antiproliferativnim delovanjem
Azra Ahmić, 2022, master's thesis/paper

Keywords: rak, molekularni šaperoni, protein toplotnega šoka, Hsp90, piperidin, zaviralec
Full text (file, 1,91 MB)

4. Sinteza 4-((3,5-dimetil-1H-pirazol-1-il)metil)benzamidnih zaviralcev encima InhA
Živa Zajec, 2019, master's thesis/paper

Keywords: tuberkuloza, zaviralci encima InhA, benzamidni zviralci InhA, 4-((3, 5-dimetil-1H-pirazol-1-il)metilbenzamidi
Full text (file, 2,29 MB)

5. Sinteza zaviralcev C-končne domene Hsp90 s tieno[2,3-b]piridinskim ogrodjem
Anja Grošelj, 2022, master's thesis/paper

Keywords: rak, Hsp90, zaviralec, tieno[2, 3-b]piridin.
Full text (file, 1,47 MB)

6. Načrtovanje, sinteza in biološko vrednotenje novih alosteričnih zaviralcev Hsp90 s protitumornim delovanjem
Živa Zajec, 2023, doctoral dissertation

Keywords: Hsp90, rak, zaviralci, alosterični, virtualno rešetanje, molekulsko modeliranje
Full text (file, 35,52 MB)

7. Discovery of novel Hsp90 C-terminal inhibitors using 3D-pharmacophores derived from molecular dynamics simulations
Tihomir Tomašič, Martina Durcik, Bradley M. Keegan, Darja Gramec, Živa Zajec, Brian S. J. Blagg, Sharon D. Bryant, 2020, original scientific article

Keywords: allosteric, cancer, Hsp90, inhibitor, molecular dynamics, pharmacophores, virtual screening
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8. Structure-activity relationships of benzothiazole-based Hsp90 C-terminal-domain inhibitors
Jaka Dernovšek, Živa Zajec, Martina Durcik, Lucija Peterlin-Mašič, Martina Gobec, Nace Zidar, Tihomir Tomašič, 2021, original scientific article

Keywords: allostery, Hsp90, benzothiazole, cancer, inhibitor, cancer therapy
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9. Exploration and optimisation of structure-activity relationships of new triazole-based C-terminal Hsp90 inhibitors towards in vivo anticancer potency
Jaka Dernovšek, Živa Zajec, Dunja Urbančič, Irena Mlinarič-Raščan, Andrej Emanuel Cotman, Nace Zidar, Tihomir Tomašič, 2024, original scientific article

Keywords: cancer, Hsp90, inhibitor, Ewing sarcoma, zebrafish
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10. ATP-competitive inhibitors of human DNA topoisomerase IIα with improved antiproliferative activity based on N-phenylpyrrolamide scaffold
Žiga Skok, Martina Durcik, Živa Zajec, Darja Gramec, Krištof Bozovičar, Anja Pišlar, Tihomir Tomašič, Anamarija Zega, Lucija Peterlin-Mašič, Danijel Kikelj, Nace Zidar, Janez Ilaš, 2023, original scientific article

Keywords: anticancer drugs, ATP-competitive inhibitors, catalytic inhibitor, cytotoxicity, human DNA topoisomerase II
Full text (file, 2,83 MB) This document has more files! More...
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