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3. New dual inhibitors of bacterial topoisomerases with broad-spectrum antibacterial activity and in vivo efficacy against vancomycin-intermediate Staphylococcus aureusMartina Durcik, Andrej Emanuel Cotman, Žan Toplak, Štefan Možina, Žiga Skok, Maria Vittoria Piras, Nace Zidar, Janez Ilaš, Anamarija Zega, Jurij Trontelj, Danijel Kikelj, Tihomir Tomašič, Lucija Peterlin-Mašič, 2023, original scientific article Keywords: antibacterial activity, bacteria, inhibitors, genetics, inhibition, peptides and proteins Full text (file, 4,53 MB) This document has more files! More... |
4. Discovery of K$_V$1.3 ion channel inhibitorsŠpela Gubič, Louise Antonia Hendrickx, Žan Toplak, Maša Sterle, Steve Peigneur, Tihomir Tomašič, Luis A. Pardo, Jan Tytgat, Anamarija Zega, Lucija Peterlin-Mašič, 2021, review article Keywords: K$_V$1.3 channel, design of K$_V$1.3 inhibitors, mitochondrial K$_V$1.3, peptide inhibitors, small-molecule inhibitors Full text (file, 6,21 MB) This document has more files! More... |
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6. Hybrid inhibitors of DNA gyrase A and BMartina Durcik, Žiga Skok, Janez Ilaš, Nace Zidar, Anamarija Zega, Petra Szili, Gábor Draskovits, T. Revesz, Danijel Kikelj, Ákos Nyerges, Csaba Pál, Lucija Peterlin-Mašič, Tihomir Tomašič, 2021, original scientific article Keywords: antibacterial, ciprofloxacin, DNA gyrase, dual inhibitor, hybrid Full text (file, 3,42 MB) This document has more files! More... |
7. ATP-competitive inhibitors of human DNA topoisomerase IIα with improved antiproliferative activity based on N-phenylpyrrolamide scaffoldŽiga Skok, Martina Durcik, Živa Zajec, Darja Gramec, Krištof Bozovičar, Anja Pišlar, Tihomir Tomašič, Anamarija Zega, Lucija Peterlin-Mašič, Danijel Kikelj, Nace Zidar, Janez Ilaš, 2023, original scientific article Keywords: anticancer drugs, ATP-competitive inhibitors, catalytic inhibitor, cytotoxicity, human DNA topoisomerase II Full text (file, 2,83 MB) This document has more files! More... |
8. Načrtovanje zaviralcev katepsina K in avtolizina s pomočjo pristopov kemometrije in strukturno podprtega načrtovanjaJure Borišek, 2015, doctoral dissertation Keywords: farmacevtska kemija, katepsin K, avtolizin E, zaviralci, balicatib, vrednotenje, načrtovanje, kemijska struktura, klinične raziskave, neželeni učinki, lizosomotropizem, osteoporoza, zdravljenje, kemometrija, disertacije Full text (file, 4,71 MB) |
9. Napovedovanje antioksidativne aktivnosti in transmembranskega transporta derivatov pulvinske kisline in kumarinaRok Martinčič, 2015, doctoral dissertation Keywords: antioksidanti, pulvinska kislina, kumarin, derivati, antioksidativna aktivnost, transmembranski transport, bilitranslokaza, računalniško modeliranje, disertacije Full text (file, 4,69 MB) |
10. Improved N-phenylpyrrolamide inhibitors of DNA gyrase as antibacterial agents for high-priority bacterial strainsNace Zidar, Alessia Onali, Peter Peršolja, Davide Benedetto Tiz, Jaka Dernovšek, Žiga Skok, Martina Durcik, Andrej Emanuel Cotman, Martina Hrast, Anamarija Zega, Lucija Peterlin-Mašič, Janez Ilaš, Tihomir Tomašič, Danijel Kikelj, 2024, original scientific article Keywords: antibacterial agents, DNA gyrase, GyrB, inhibitor, N-phenylpyrrolamide, ParE, topoisomerase IV Full text (file, 2,78 MB) This document has more files! More... |