21. Amide containing NBTI antibacterials with reduced hERG inhibition, retained antimicrobial activity against gram-positive bacteria and in vivo efficacyMaja Kokot, Matjaž Weiss, Irena Zdovc, Lidija Senerovic, Natasa Radakovic, Marko Anderluh, Nikola Minovski, Martina Hrast, 2023, original scientific article Keywords: NBTIs, DNA gyrase, topoisomerase IV, antibacterials, MRSA, hERG inhibition, in vivo efficacy Full text (file, 3,61 MB) This document has more files! More... |
22. Intracellular hydrolysis of small-molecule O-linked N-acetylglucosamine transferase inhibitors differs among cells and is not required for its inhibitionElena Maria Loi, Matjaž Weiss, Stane Pajk, Martina Gobec, Tihomir Tomašič, Roland J. Pieters, Marko Anderluh, 2020, original scientific article Keywords: ester hydrolysis, inhibitor, O-GlcNAc transferase, OGT inhibitor Full text (file, 1,90 MB) This document has more files! More... |
23. Inhibition of O-GlcNAc transferase alters the differentiation and maturation process of human monocyte derived dendritic cellsMatjaž Weiss, Marko Anderluh, Martina Gobec, 2021, original scientific article Keywords: O-GlcNAcylation, O-GlcNAc transferase (OGT), monocyte derived DCs, OSMI-1, immunometabolism, pharmaceutical chemistry Full text (file, 2,84 MB) This document has more files! More... |
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25. Structurally optimized potent dual-targeting NBTI antibacterials with an enhanced bifurcated halogen-bonding propensityMaja Kokot, Matjaž Weiss, Irena Zdovc, Martina Hrast, Marko Anderluh, Nikola Minovski, 2021, original scientific article Keywords: NBTIs, DNA gyrase, topoisomerase IV, bifurcated halogen bonds, dual targeting Full text (file, 2,92 MB) This document has more files! More... |
26. New quinolinone O-GlcNAc transferase inhibitors based on fragment growthMatjaž Weiss, Elena Maria Loi, Maša Sterle, Cyril Balsollier, Tihomir Tomašič, Roland J. Pieters, Martina Gobec, Marko Anderluh, 2021, original scientific article Keywords: O-GlcNAc, O-GlcNAc transferase, protein glycosylation, fragments growth, molecular docking Full text (file, 1,37 MB) This document has more files! More... |
27. Covalently conjugated NOD2/TLR7 agonists are potent and versatile immune potentiatorsSamo Guzelj, Matjaž Weiss, Bram Slütter, Ruža Frkanec, Žiga Jakopin, 2022, original scientific article Keywords: immunostimulatory activity, vaccines, immune responses, pattern recognition receptors, synthesis of NOD2 agonist, Toll-like receptor 7 Full text (file, 4,87 MB) This document has more files! More... |
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