1. Action of clathrodin and analogues on voltage-gated sodium channelsSteve Peigneur, Aleš Žula, Nace Zidar, Fiona Chan-Porter, Robert Kirby, David J. Madge, Janez Ilaš, Danijel Kikelj, Jan Tytgat, 2014, original scientific article Keywords: clathrodin, oroidin, hymenidin, voltage-gated sodium channels, sodium channel modulator, sponge Full text (file, 738,85 KB) This document has more files! More... |
2. Discovery of K$_V$1.3 ion channel inhibitorsŠpela Gubič, Louise Antonia Hendrickx, Žan Toplak, Maša Sterle, Steve Peigneur, Tihomir Tomašič, Luis A. Pardo, Jan Tytgat, Anamarija Zega, Lucija Peterlin-Mašič, 2021, review article Keywords: K$_V$1.3 channel, design of K$_V$1.3 inhibitors, mitochondrial K$_V$1.3, peptide inhibitors, small-molecule inhibitors Full text (file, 6,21 MB) This document has more files! More... |
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5. 3D pharmacophore-based discovery of novel Kv10.1 inhibitors with antiproliferative activityŽan Toplak, Louise Antonia Hendrickx, Špela Gubič, Štefan Možina, Bojana Žegura, Alja Štern, Matjaž Novak, Xiaoyi Shi, Steve Peigneur, Jan Tytgat, Tihomir Tomašič, Luis A. Pardo, Lucija Peterlin-Mašič, 2021, original scientific article Keywords: K$_V$10.1, ion channels, hERG, pharmacophore modelling, virtual screening, antiproliferative activity Full text (file, 14,79 MB) This document has more files! More... |
6. New diarylamine KV10.1 inhibitors and their anticancer potentialŠpela Gubič, Žan Toplak, Xiaoyi Shi, Jaka Dernovšek, Louise Antonia Hendrickx, Ernesto Lopes Pinheiro-Junior, Steve Peigneur, Jan Tytgat, Luis A. Pardo, Lucija Peterlin-Mašič, Tihomir Tomašič, 2022, original scientific article Keywords: KV10.1, ion channels, hERG, SAR, antiproliferative activity Full text (file, 869,51 KB) This document has more files! More... |
7. New aryl and acylsulfonamides as state-dependent inhibitors of Na$_v$1.3 voltage-gated sodium channelNace Zidar, Tihomir Tomašič, Danijel Kikelj, Martina Durcik, Jan Tytgat, Steve Peigneur, Marc Rogers, Alexander Haworth, Robert W. Kirby, 2023, original scientific article Keywords: voltage-gated sodium channel, Na$_v$ channel, Na$_v$1.3, inhibitor, arylsulfonamide, acylsulfonamide Full text (file, 2,36 MB) This document has more files! More... |
8. Attenuation of Nicotine Effects on A549 Lung Cancer Cells by Synthetic α7 nAChR Antagonists APS7-2 and APS8-2Ahmad Joukhan, Veno Kononenko, Tadeja Bele, Marija Sollner Dolenc, Steve Peigneur, Ernesto Lopes Pinheiro-Junior, Jan Tytgat, Tom Turk, Igor Križaj, Damjana Drobne, 2024, original scientific article Keywords: marine toxin, nicotinic acetylcholine receptor, nAChR antagonist, APS7-2, APS8-2 Full text (file, 6,98 MB) This document has more files! More... |
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