1. Synthesis of 3-amino-4-substituted monocyclic ß-lactams—important structural motifs in medicinal chemistryKatarina Grabrijan, Nika Strašek Benedik, Stanislav Gobec, 2022, original scientific article Keywords: monocyclic ß-lactam, Staudinger [2+2] cyclocondensation, cerium ammonium nitrate, hydrazine hydrate, 3-amino-4-substituted azetidin-2-one, inhibitory activities Full text (file, 3,51 MB) This document has more files! More... |
2. Simulation- and AI-directed optimization of 4,6-substituted 1,3,5-triazin-2(1H)-ones as inhibitors of human DNA topoisomerase IIαBarbara Herlah, Tjaša Goričan, Nika Strašek Benedik, Simona Golič Grdadolnik, Izidor Sosič, Andrej Perdih, 2024, original scientific article Keywords: molecular design, molecular simulations, deep learning, human DNA, topoisomerase IIα, catalytic inhibitors, anticancer agents Full text (file, 10,65 MB) This document has more files! More... |
3. Tunable heteroaromatic nitriles for selective bioorthogonal click reaction with cysteineMatic Proj, Nika Strašek Benedik, Stane Pajk, Damijan Knez, Izidor Sosič, 2023, original scientific article Keywords: labeling, monomers, nitrogen compounds, peptides, reactivity, proteins Full text (file, 4,39 MB) This document has more files! More... |
4. Discovery of compounds with viscosity-reducing effects on biopharmaceutical formulations with monoclonal antibodiesMatic Proj, Mitja Zidar, Blaž Lebar, Nika Strašek Benedik, Goran Miličić, Aleš Žula, Stanislav Gobec, 2022, original scientific article Keywords: viscosity, protein formulations, biopharmaceuticals, viscosity-reducing agents, computational screening Full text (file, 2,19 MB) This document has more files! More... |
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