1. Discovery of a new drug-like series of OGT inhibitors by virtual screeningElena Maria Loi, Tihomir Tomašič, Cyril Balsollier, Kevin van Eekelen, Matjaž Weiss, Martina Gobec, Matthew G Alteen, David J. Vocadlo, Roland J. Pieters, Marko Anderluh, 2022, original scientific article Keywords: O-GlcNAc transferase, OGT inhibitors, virtual screening, pharmaceutical chemistry Full text (file, 10,66 MB) This document has more files! More... |
2. Strukturno podprto načrtovanje, sinteza in biološko vrednotenje novih zaviralcev O-β-N-acetilglukozaminil transferazeElena Maria Loi, 2023, doctoral dissertation Keywords: O-GlcNAcylation, OGT, OGA, OGT inhibitors, posttranslational, modifications, computational drug design, virtual screening, ester hydrolysis, metabolic stability Full text (file, 20,68 MB) |
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6. Intracellular hydrolysis of small-molecule O-linked N-acetylglucosamine transferase inhibitors differs among cells and is not required for its inhibitionElena Maria Loi, Matjaž Weiss, Stane Pajk, Martina Gobec, Tihomir Tomašič, Roland J. Pieters, Marko Anderluh, 2020, original scientific article Keywords: ester hydrolysis, inhibitor, O-GlcNAc transferase, OGT inhibitor Full text (file, 1,90 MB) This document has more files! More... |
7. Overview of the assays to probe O-linked β-N-acetylglucosamine transferase binding and activityCyril Balsollier, Roland J. Pieters, Marko Anderluh, 2021, review article Keywords: OGT, GlcNAcylation, O-GlcNAc transferase, bioassay, OGT inhibitor Full text (file, 5,14 MB) This document has more files! More... |
8. New quinolinone O-GlcNAc transferase inhibitors based on fragment growthMatjaž Weiss, Elena Maria Loi, Maša Sterle, Cyril Balsollier, Tihomir Tomašič, Roland J. Pieters, Martina Gobec, Marko Anderluh, 2021, original scientific article Keywords: O-GlcNAc, O-GlcNAc transferase, protein glycosylation, fragments growth, molecular docking Full text (file, 1,37 MB) This document has more files! More... |
9. Strukturno podprto načrtovanje, sinteza in biološko vrednotenje novih zaviralcev O-β-N-acetilglukozaminil transferazeElena Maria Loi, 2023, doctoral dissertation Keywords: O-GlcNAcylation, OGT, OGA, OGT inhibitors, posttranslational modifications, computational drug design, virtual screening, ester hydrolysis, metabolic stability. Full text (file, 20,68 MB) |
10. Uporaba bioloških in računalniških orodij za načrtovanje, testiranje in sintezo novih zaviralcev β-N-acetilglukozaminil transferazeCyril Balsollier, 2024, doctoral dissertation Keywords: OGT, O-GlcNAcylation, medicinska kemija, računalniška kemija, biološki preskusi, biokemija, organska kemija Full text (file, 7,35 MB) |