61. Nucleotide-binding oligomerization domain 1/Toll-like receptor 4 co-engagement promotes non-specific immune response against K562 cancer cellsSamo Guzelj, Žiga Jakopin, 2022, original scientific article Keywords: NOD1 agonist, TLR4 agonist, LPS, synergy, cytolytic activity, PBMC, NK cells, K562 Full text (file, 1,74 MB) This document has more files! More... |
62. Synthesis of conformationally constrained D-Glu-meso-DAP analogs as innate immune agonistsSamo Guzelj, Žiga Jakopin, 2020, original scientific article Keywords: NOD1 agonist, constrained meso-DAP mimetics, NOD1 activation, innate immune agonist, bioisosteric replacement, rigidization Full text (file, 1,65 MB) This document has more files! More... |
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65. Design and synthesis of novel 3-triazolyl-1-thiogalactosides as galectin-1, -3 and -8 inhibitorsSjors van Klaveren, Jaka Dernovšek, Žiga Jakopin, Marko Anderluh, Hakon Leffler, Ulf Nilsson, Tihomir Tomašič, 2022, original scientific article Full text (file, 1010,75 KB) This document has more files! More... |
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69. Discovery of desmuramylpeptide NOD2 agonists with single-digit nanomolar potencySamo Guzelj, Špela Bizjak, Žiga Jakopin, 2022, original scientific article Keywords: NOD2, desmuramylpeptide, immunostimulant, adamantane, PBMC cytotoxicity, K562, agonists, cells, peptides and proteins, reaction products, toxicological synergy Full text (file, 2,68 MB) This document has more files! More... |
70. Structural fine-tuning of desmuramylpeptide NOD2 agonists defines their in vivo adjuvant activitySamo Guzelj, Sanja Nabergoj, Martina Gobec, Stane Pajk, Veronika Weiss, Bram Slütter, Ruža Frkanec, Adela Štimac, Primož Šket, Janez Plavec, Irena Mlinarič-Raščan, Žiga Jakopin, 2021, original scientific article Keywords: reaction products, peptides, proteins, cells, organic compounds, toxicity Full text (file, 7,19 MB) This document has more files! More... |