31. Biopharmaceutical classification of desloratadine - not all drugs are classified the easy wayKatja Berginc, Nadica Sibinovska, Simon Žakelj, Jurij Trontelj, Igor Legen, 2020, original scientific article Keywords: desloratadine, BCS-based bio-waiver, luminal stability, permeability, dissolution Full text (file, 433,79 KB) This document has more files! More... |
32. Stereoselective activity of 1-propargyl-4-styrylpiperidine-like analogues that can discriminate between monoamine oxidase isoforms A and BDamijan Knez, Natalia Colettis, Luca G. Iacovino, Matej Sova, Anja Pišlar, Janez Konc, Samo Lešnik, Josefina Higgs, Fabiola Kamecki, Irene Mangialavori, Ana Dolšak, Simon Žakelj, Jurij Trontelj, Janko Kos, Claudia Binda, Nora Marder Mariel, Stanislav Gobec, 2020, original scientific article Keywords: binding energy, ethyl groups, inhibition, inhibitors, molecular structure Full text (file, 6,41 MB) This document has more files! More... |
33. Proof-of-concept for a miniaturized shake-flask biopharmaceutical solubility determination by sonic mixingArdita Veseli, Albin Kristl, Simon Žakelj, 2020, original scientific article Keywords: pharmacokinetics, physiologically based pharmacokinetic (PBPK) modeling gastro plus modeling, clinical trial simulation(s), bioequivalence, biopharmaceutics classification system (BCS), virtual bioequivalence (VBE) Full text (file, 565,27 KB) This document has more files! More... |
34. 8-Hydroxyquinolylnitrones as multifunctional ligands for the therapy of neurodegenerative diseasesDamijan Knez, Anže Meden, Anja Pišlar, Janko Kos, Simon Žakelj, Jure Stojan, Stanislav Gobec, José Marco-Contelles, 2023, original scientific article Keywords: quinolylnitrone, butyrylcholinesterase, monoamine oxidase B, Alzheimer's disease, multifunctional ligands, 6-hydroxydopamine model, passive avoidance task, novel object recognition Full text (file, 3,96 MB) This document has more files! More... |
35. How azide ion/hydrazoic acid passes through biological membranesSimona Lojevec Hartl, Simon Žakelj, Marija Sollner Dolenc, Vladimir Smrkolj, Janez Mavri, 2023, original scientific article Keywords: azide ion, hydrazoic acid, octanol/water partition coefficient, effective permeability, PAMPA, diffusion, inhibition, cytochrome c oxidase complex IV Full text (file, 985,33 KB) This document has more files! More... |
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