Cancer is one of the most common diseases in the world and in the last few decades, we are going thru the rise of new ways of treating cancer. Immunotherapy is a method, which forces the body to start fighting against cancer cells. One perspective method is dendritic cells, which serve as antigen-presenting cells and activate T cell immune
response. They have identified few antigens on tumors, that are different than on healthy cells. They have developed many methods to pack those antigens into dendritic cells.
This paper covers the fusion method because we can pack the whole set of tumor antigens into dendritic cells. We can use dendritic cells that originate from a patient itself or are commercially produced and available for more patients. These therapies are classified as anti-cancer vaccines because with the insertion of antigens (through antigen-presenting cells) they activate an immune response. There were a lot of clinical trials surrounding these vaccines, but the problem is low efficiency. The use of patients'cells is creating more specific drugs and is showing a shift of medicine to personalized medicine.
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