Mycophenolate mofetile is half-synthetic active substance used for suppression of immune response in organ transplantation (kidney, heart, liver). For the purpose of analytic control, specific impurities as analytical standards are needed. In the diploma thesis we dealt with the synthesis of one of the impurities of mycophenolate mofetil, namely oxalate morpholinoethyl ether mycophenolate mofetil, which was synthesized in two steps according to the procedure from the literature. The synthesis was also performed on a larger scale, where we obtained higher yields of the product. The experimental part was completed by hydrolysis of the synthesized compound under acidic (HCl) and basic (NaOH, LiOH) conditions.
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