Your browser does not allow JavaScript!
JavaScript is necessary for the proper functioning of this website. Please enable JavaScript or use a modern browser.
Open Science Slovenia
Open Science
DiKUL
slv
|
eng
Search
Browse
New in RUL
About RUL
In numbers
Help
Sign in
Organisation
Files
Mentors
Basic
Bibliography
Published theses
Top keywords
Keyword timeline
Co-mentors
Bibliography of the person, including all types of documents, not only theses.
PhD theses (2)
Žiga Skok:
Načrtovanje, sinteza in vrednotenje novih ATP-kompetitivnih zaviralcev človeške DNA-topoizomeraze II kot potencialnih protirakavih učinkovin
Davide Benedetto Tiz:
Razvoj novih N-fenilpirolamidov kot zaviralcev DNA-giraze in topoizomeraze IV
MSc theses (7)
Nataša Šijanec:
Načrtovanje in sinteza 3,4-dikloro-5-metilpirolamidnih zaviralcev DNA giraze B
Anja Sirc:
Razvoj 4,5-dibromopirolamidov kot ATP kompetitivnih zaviralcev DNA giraze B
Helena Macut:
Načrtovanje in sinteza novih 4,5-dibromo-N-fenil-1H-pirol-2-karboksiamidnih in N-fenil-1H-indol-2-karboksiamidnih zaviralcev DNA giraze B
Nataša Turk:
Sinteza in vrednotenje novih N-(4-karbamoilfenil)pirolamidnih zaviralcev človeške DNA-topoizomeraze II
Martina Durcik:
Načrtovanje in sinteza novih N-fenilpirolamidnih zaviralcev DNA-giraze B
Barbara Herlah:
Sinteza in vrednotenje piperazinskih in piperidinskih derivatov N-fenilpirolamidov kot zaviralcev DNA-giraze B
Nataša Šijanec:
Načrtovanje in sinteza 3,4-dikloro-5-metilpirolamidnih zaviralcev DNA giraze B
BSc theses (3)
Lea Seljak:
Sinteza in vrednotenje antioksidativnih lastnosti derivatov 5-benzilidenbarbiturne in 5-benzilidentiobarbiturne kisline
Valerija Janežič:
Sinteza substituiranih 5,5'-(fenilmetilen)bis(barbituratov) in 5,5'(fenilmetilen)bis(tiobarbituratov) in določanje njihovega antioksidativnega delovanja
Ana Čelhar:
Sinteza 5-fenil-1,5-dihidro-pirano [2,3-d]pirimidin-2,4-dionov in 5-benzoilpirimidin-2,4,6-trionov ter vrednotenje njihovih antioksidativnih lastnosti
Other documents (26)
Anja Pišlar, Biljana Božić Nedeljković, Mina Perić, Tanja Jakoš, Nace Zidar, Janko Kos:
Cysteine peptidase cathepsin X as a therapeutic target for simultaneous TLR3/4-mediated microglia activation
Steve Peigneur, Aleš Žula, Nace Zidar, Fiona Chan-Porter, Robert Kirby, David J. Madge, Janez Ilaš, Danijel Kikelj, Jan Tytgat:
Action of clathrodin and analogues on voltage-gated sodium channels
Tihomir Tomašič, Matic Mirt, Michaela Barančokova, Janez Ilaš, Nace Zidar, Päivi Tammela, Danijel Kikelj:
Design, synthesis and biological evaluation of 4,5-dibromo-N-(thiazol-2-yl)-1H-pyrrole-2-carboxamide derivatives as novel DNA gyrase inhibitors
Martina Durcik, Päivi Tammela, Michaela Barančokova, Tihomir Tomašič, Janez Ilaš, Danijel Kikelj, Nace Zidar:
Synthesis and evaluation of N-phenylpyrrolamides as DNA gyrase B inhibitors
Bernarda Majc, Anamarija Habič, Metka Novak, Ana Rotter, Andrej Porčnik, Jernej Mlakar, Vera Župunski, Urša Pečar Fonović, Damijan Knez, Nace Zidar, Stanislav Gobec, Janko Kos, Tamara Lah Turnšek, Anja Pišlar, Barbara Breznik:
Upregulation of cathepsin X in glioblastoma
Martina Durcik, Andrej Emanuel Cotman, Žan Toplak, Štefan Možina, Žiga Skok, Maria Vittoria Piras, Nace Zidar, Janez Ilaš, Anamarija Zega, Jurij Trontelj, Danijel Kikelj, Tihomir Tomašič, Lucija Peterlin-Mašič:
New dual inhibitors of bacterial topoisomerases with broad-spectrum antibacterial activity and in vivo efficacy against vancomycin-intermediate Staphylococcus aureus
Jaka Dernovšek, Živa Zajec, Martina Durcik, Lucija Peterlin-Mašič, Martina Gobec, Nace Zidar, Tihomir Tomašič:
Structure-activity relationships of benzothiazole-based Hsp90 C-terminal-domain inhibitors
Anja Pišlar, Larisa Tratnjek, Gordana Glavan, Nace Zidar, Marko Živin, Janko Kos:
Neuroinflammation-induced upregulation of glial cathepsin X expression and activity in vivo
Jaka Dernovšek, Živa Zajec, Goran Poje, Dunja Urbančič, Tjaša Goričan, Simona Golič Grdadolnik, Irena Mlinarič-Raščan, Andrej Emanuel Cotman, Nace Zidar, Tihomir Tomašič:
Exploration and optimisation of structure-activity relationships of new triazole-based C-terminal Hsp90 inhibitors towards in vivo anticancer potency
Žiga Skok, Martina Durcik, Živa Zajec, Darja Gramec, Krištof Bozovičar, Anja Pišlar, Tihomir Tomašič, Anamarija Zega, Lucija Peterlin-Mašič, Danijel Kikelj, Nace Zidar, Janez Ilaš:
ATP-competitive inhibitors of human DNA topoisomerase IIα with improved antiproliferative activity based on N-phenylpyrrolamide scaffold
Nace Zidar, Alessia Onali, Peter Peršolja, Davide Benedetto Tiz, Jaka Dernovšek, Žiga Skok, Martina Durcik, Andrej Emanuel Cotman, Martina Hrast, Anamarija Zega, Lucija Peterlin-Mašič, Janez Ilaš, Tihomir Tomašič, Danijel Kikelj:
Improved N-phenylpyrrolamide inhibitors of DNA gyrase as antibacterial agents for high-priority bacterial strains
Nace Zidar, Sofia Montalvão, Žiga Hodnik, Dorota A. Nawrot, Aleš Žula, Janez Ilaš, Danijel Kikelj, Päivi Tammela, Lucija Peterlin-Mašič:
Antimicrobial activity of the marine alkaloids, clathrodin and oroidin, and their synthetic analogues
Martina Durcik, Žiga Skok, Janez Ilaš, Nace Zidar, Anamarija Zega, Petra Szili, Gábor Draskovits, T. Revesz, Danijel Kikelj, Ákos Nyerges, Csaba Pál, Lucija Peterlin-Mašič, Tihomir Tomašič:
Hybrid inhibitors of DNA gyrase A and B
Nace Zidar, Daniela Secci, Tihomir Tomašič, Lucija Peterlin-Mašič, Danijel Kikelj, Daniele Passarella, Aida Nelly Garcia Argaez, Mariafrancesca Hyeraci, Lisa Via Dalla:
Synthesis, antiproliferative effect and topoisomerase II inhibitory activity of 3-methyl-2-phenyl-1H-indoles
Žiga Skok, Michaela Barančokova, Ondřej Benek, Cristina Durante Cruz, Päivi Tammela, Tihomir Tomašič, Nace Zidar, Lucija Peterlin-Mašič, Anamarija Zega, Danijel Kikelj, Janez Ilaš:
Exploring the chemical space of benzothiazole-based DNA gyrase B inhibitors
Martina Durcik, Žan Toplak, Nace Zidar, Janez Ilaš, Anamarija Zega, Danijel Kikelj, Lucija Peterlin-Mašič, Tihomir Tomašič:
Efficient synthesis of hydroxy-substituted 2-aminobenzo[d]thiazole-6-carboxylic acid derivatives as new building blocks in drug discovery
Ákos Nyerges, Tihomir Tomašič, Martina Durcik, T. Revesz, Petra Szili, Žiga Skok, Nace Zidar, Janez Ilaš, Anamarija Zega, Danijel Kikelj, Lucija Peterlin-Mašič:
Rational design of balanced dual-targeting antibiotics with limited resistance
Andrej Emanuel Cotman, Martina Durcik, Davide Benedetto Tiz, Federica Fulgheri, Daniela Secci, Maša Sterle, Štefan Možina, Žiga Skok, Nace Zidar, Anamarija Zega, Janez Ilaš, Lucija Peterlin-Mašič, Tihomir Tomašič, Danijel Kikelj:
Discovery and hit-to-lead optimization of benzothiazole scaffold-based DNA gyrase inhibitors with potent activity against Acinetobacter baumannii and Pseudomonas aeruginosa
Nace Zidar, Tihomir Tomašič, Danijel Kikelj, Martina Durcik, Jan Tytgat, Steve Peigneur, Marc Rogers, Alexander Haworth, Robert W. Kirby:
New aryl and acylsulfonamides as state-dependent inhibitors of Na$_v$1.3 voltage-gated sodium channel
Maša Sterle, Martina Durcik, Danijel Kikelj, Nace Zidar, Lucija Peterlin-Mašič, Janez Ilaš, Tihomir Tomašič, Andrej Emanuel Cotman, Anamarija Zega:
Exploring the 5-substituted 2-aminobenzothiazole-based DNA gyrase B inhibitors active against ESKAPE pathogens
Nace Zidar, Andrej Emanuel Cotman, Wessel Sinnige, Ondřej Benek, Michaela Barančokova, Anamarija Zega, Lucija Peterlin-Mašič, Tihomir Tomašič, Janez Ilaš, Ricardo D. Enriz, Danijel Kikelj:
Exploring the interaction of N-(benzothiazol-2-yl)pyrrolamide DNA gyrase inhibitors with the GyrB ATP-binding site lipophilic floor
Martina Piga, Zoltán Varga, Ádám Fehér, Ferenc Papp, Eva Korpos Pintye-Gyuri, Kavya C. Bangera, Rok Frlan, Janez Ilaš, Jaka Dernovšek, Tihomir Tomašič, Nace Zidar:
Identification of a novel structural class of H$_v$1 inhibitors by structure-based virtual screening
Andrej Emanuel Cotman, Federica Fulgheri, Martina Piga, Peter Peršolja, Davide Benedetto Tiz, Žiga Skok, Martina Durcik, Maša Sterle, Jaka Dernovšek, Anamarija Zega, Lucija Peterlin-Mašič, Janez Ilaš, Tihomir Tomašič, Danijel Kikelj, Nace Zidar:
New N-phenylpyrrolamide inhibitors of DNA gyrase with improved antibacterial activity
Jaka Dernovšek, Živa Zajec, Dunja Urbančič, Ana Jug, Žiga Skok, Janez Ilaš, Nace Zidar, Tihomir Tomašič:
Hiding in plain sight
Jaka Dernovšek, Dunja Urbančič, Živa Zajec, Žiga Skok, Janez Ilaš, Nace Zidar, Tihomir Tomašič:
First dual inhibitors of human topoisomerase IIα and Hsp90 C-terminal domain inhibit the growth of Ewing sarcoma in vitro and in vivo
Maša Zorman, Maja Kokot, Irena Zdovc, Lidija Šenerović, Mina Mandic, Nace Zidar, Andrej Emanuel Cotman, Martina Durcik, Lucija Peterlin-Mašič, Nikola Minovski, Marko Anderluh, Martina Hrast:
Enhancing antibacterial efficacy