Introduction: The prostheses for replacing parts of the face are facial prostheses, also known as epitheses. It is considered they are well-designed when a random observer cannot notice anything that would indicate a prosthetic reconstruction. The success of the manufacturing of a prosthesis depends on precise planning and design, manufacturing techniques and the materials from which the prosthesis is made. Silicone is the most known material for manufacture of facial prostheses. By adding different supplements into the silicone, we can improve its properties. Appropriate hygiene is the key to prevent infections of surrounding tissues. The main reasons for the deterioration of epithesis properties are the exposure to UV light, environmental pollution, high humidity, temperature changes and hygiene products. Purpose: The aim of the thesis is to investigate the effects of various disinfectants on the properties of silicone epitheses. Methods: The thesis is based on a descriptive research of the literature and offers a review of the literature in the field of subject matter. Results: The smallest colour change was noticed in studies that involved silicon MDX 4-4210 with various supplements. Data about the disinfection and accelerated ageing were summarized. After description of the procedures used, the data on the effects of various disinfectants: neutral soap, effervescent tablets and chlorhexidine on the colour stability and hardness of silicone was presented. Average values for these results were calculated. We have found that the smallest colour change was noticed on the silicone with the addition of Ba(SO)4 after disinfection with neutral soap solution, while the greatest colour change was noticed on the material with the addition of »makeup« after disinfection with neutral soap solution. The lowest hardness of silicone was found in samples of silicone with the addition of TiO2 after disinfection with neutral soap solution, while the highest hardness was measured on silicone with the addition of ceramic dust after disinfection with neutral soap and with the addition of »makeup« dust after disinfection with effervescent tablets. Discussion and conclusion: The supplements have an influence on silicone, which was shown after the change of characteristic of silicon after disinfection. Based on the results, we may conclude that in order to choose the most appropriate disinfectant product it is necessary to know the properties of material and the supplements in silicone.
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