MERJENJE MAJHNIH PRETOKOV TEKOČIN V MIKROFLUIDNIH SISTEMIH

PLANKAR, JERNEJ (author), Možek, Matej (mentor)

Moderni mikrofluidni laboratorij na čipu (ang. Lab-On-Chip, LOC) zdruţuje mikroelektronsko tehnologijo z naprednimi tehnikami iz biokemijskega, farmacijskega in drugih področij. Skladno z zmanjševanjem dimenzij LOC sistemov se povečuje potreba natančnem merjenju majhnih pretokov tekočin. Opisani so merilni pristopi za meritev pretoka tekočin v LOC sistemih. Podan je pregled tipičnih pristopov k realizaciji merilnikov majhnih pretokov (< 1 ml/min). Opisan je razvoj optičnega merilnika pretoka. Pri tem sta upoštevani moţnosti uporabe merilnika za posamični in kontinuirani način meritev. Za oba načina je ugotovljena natančnost merilnika. Na osebnem računalniku je programiran vmesnik, ki omogoča enostavno nastavitev, merjenje in umerjanje izdelanega merilnika pretoka. Vmesnik je uporabljen pri izdelavi programske opreme sistema za samodejno karakterizacijo mikročrpalk s preletom frekvenc in amplitud signala vzbujanja ter beleţenjem tlaka in pretoka.

• Language: Slovenian
• Keywords: mikročrpalka, pretok, kapilara, meniskus, mikrokanal, fototranzistor, mikrokrmilnik, prekinitev, karakterizacija
• Work type: Undergraduate thesis
• Organization: FE - Faculty of Electrical Engineering
• Year: 2014
• PID: 20.500.12556/RUL-29975
• Publication date in RUL: 22.10.2014

Secondary language

• Language: English
• Title: MEASUREMENT OF SMALL LIQUID FLOW IN MICROFLUIDIC SYSTEMS

Abstract

Modern microfluidic Lab-On-Chip (LOC) combines microelectronic technology with advanced procedures from biochemistry, pharmacy and other areas. Along with size reduction of LOC systems, the need for precise measurement of small liquid flows is increasing. Concise overview of approaches to small (< 1 ml/min) liquid flow measurement in LOC systems is given, as well as their realizations. Development of optical flow rate measurement device is presented. Single measurement and continuous operation methods are taken into consideration. Accuracy of the device using both methods is evaluated. An interface for simple setting, measurement and calibration of the described measurement device was programmed on a PC. It was was used in development of an automated micropump characterization system software with frequency and amplitude sweep as well as flow and pressure logging.

• Keywords: micropump, flow, capillary, meniscus, microchannel, phototransistor, microcontroller, interrupt, characterization