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Designer cellulosomes - catalytic nanomachines with significant potential in biotechnology and circular economy
ID Vodovnik, Maša (Author)

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Abstract
Cellulosomes are multienzyme complexes originally found on the surface of certain anaerobic celluloytic bacteria and fungi that are specialized in the degradation of plant cell walls. Recently, the efficiency in lignocellulose conversion and architectural features of these intricate complexes inspired the construction of artificial chimeric complexes for targeted substrate degradation. The simultaneous advancements in synthetic biology, protein engineering, and the pursuit of greater sustainability across various industries have highlighted the immense potential of these artificially designed enzymatic complexes for diverse applications. Notably, they hold significant promise for industries specializing in valorization of plant biomass waste and the production of bio-based renewable energy. The article discusses the main architectural features, design and construction steps as well as various biotechnological applications of these intriguing nanomachines.

Language:English
Keywords:designer cellulosomes, lignocellulose valorization, protein engineering, nanobiotechnology, bio-based products
Work type:Article
Typology:1.02 - Review Article
Organization:BF - Biotechnical Faculty
Publication status:Published
Publication version:Version of Record
Year:2025
Number of pages:Str. 118-125
Numbering:Vol. 68, iss. 1
PID:20.500.12556/RUL-167409 This link opens in a new window
UDC:60:579
ISSN on article:1854-3073
DOI:10.14720/abs.68.01.21452 This link opens in a new window
COBISS.SI-ID:221901571 This link opens in a new window
Publication date in RUL:20.02.2025
Views:91
Downloads:11
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Record is a part of a journal

Title:Acta biologica slovenica
Publisher:Društvo biologov Slovenije, Založba Univerze v Ljubljani
ISSN:1854-3073
COBISS.SI-ID:221921024 This link opens in a new window

Licences

License:CC BY-SA 4.0, Creative Commons Attribution-ShareAlike 4.0 International
Link:http://creativecommons.org/licenses/by-sa/4.0/
Description:This Creative Commons license is very similar to the regular Attribution license, but requires the release of all derivative works under this same license.

Secondary language

Language:Slovenian
Keywords:biotehnologija, nanotehnologija, mikrobiologija, celulosomi, krožno gospodarstvo

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